View : 432 Download: 0

Full metadata record

DC Field Value Language
dc.contributor.author홍영미-
dc.contributor.author손세정-
dc.date.accessioned2018-02-28T16:30:12Z-
dc.date.available2018-02-28T16:30:12Z-
dc.date.issued2018-
dc.identifier.issn1738-1061-
dc.identifier.otherOAK-22073-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/240127-
dc.description.abstractPurpose: To differentiate adenoviral pharyngoconjunctival fever (PCF) from acute Kawasaki disease (KD) using laboratory tests before results of virus-real time polymerase chain reaction and ophthalmologic examination are obtained. Methods: Baseline patient characteristics and laboratory measurements were compared between 40 patients with adenovirus infection and 123 patients with KD. Results: The patients with adenovirus infection were generally older than those with KD (median: 3.9 years vs. 2 years, P=0.000). White blood cell and, platelet count, and aspartate aminotransferase, alanine aminotransferase, and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels showed significant differences between the 2 groups, but the C-reactive protein (CRP) levels did not (6.8±3.0 mg/dL vs. 8.3±5.8 mg/dL, P=0.126). In the adenovirus infection group, the CRP levels were <1, <3, <10, and ≥ 10 mg/dL in 2 (5%), 3 (7.5%), 30 (75%), and 5 patients (12.5%), respectively. The cutoff NT-proBNP level was 265 pg/mL. Discrepancy was defined as CRP and NT-proBNP levels of ≥ 3 or <3 mg/dL, and <265 or ≥265 pg/mL, respectively. Among the 35 patients with adenovirus infection whose CRP levels were ≥ 3 mg/dL, 29 (82.9%) showed a discrepancy. Conversely, of the 103 patients with KD whose CRP levels were ≥3 mg/dL, 83 (80.6%) showed no discrepancy. Between the groups, a significant difference in discrepancy rate was observed (P=0.000). None of the patients with adenovirus infection had CRP and NT-proBNP levels of < 3 mg/dL and ≥265 pg/mL, respectively. Conclusion: With a sensitivity of 82.9% and a specificity of 80.6%, CRP and NT-proBNP levels may differentiate between adenoviral PCF and acute KD. © 2018 by The Korean Pediatric Society.-
dc.languageEnglish-
dc.publisherKorean Pediatric Society-
dc.subjectAdenovirus-
dc.subjectC-reactive protein-
dc.subjectDiscrepancy-
dc.subjectKawasaki disease-
dc.subjectNT-proBNP-
dc.titleC-reactive protein and N-terminal pro-brain natriuretic peptide discrepancy: A differentiation of adenoviral pharyngoconjunctival fever from Kawasaki disease-
dc.typeArticle-
dc.relation.issue1-
dc.relation.volume61-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage12-
dc.relation.lastpage16-
dc.relation.journaltitleKorean Journal of Pediatrics-
dc.identifier.doi10.3345/kjp.2018.61.1.12-
dc.identifier.scopusid2-s2.0-85040933221-
dc.author.googleChoi J.E.-
dc.author.googleKang H.W.-
dc.author.googleHong Y.M.-
dc.author.googleSohn S.-
dc.contributor.scopusid홍영미(35210025100)-
dc.contributor.scopusid손세정(56577409300)-
dc.date.modifydate20200903081003-
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE