Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 홍영미 | * |
dc.contributor.author | 손세정 | * |
dc.date.accessioned | 2018-02-28T16:30:12Z | - |
dc.date.available | 2018-02-28T16:30:12Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 1738-1061 | * |
dc.identifier.other | OAK-22073 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/240127 | - |
dc.description.abstract | Purpose: To differentiate adenoviral pharyngoconjunctival fever (PCF) from acute Kawasaki disease (KD) using laboratory tests before results of virus-real time polymerase chain reaction and ophthalmologic examination are obtained. Methods: Baseline patient characteristics and laboratory measurements were compared between 40 patients with adenovirus infection and 123 patients with KD. Results: The patients with adenovirus infection were generally older than those with KD (median: 3.9 years vs. 2 years, P=0.000). White blood cell and, platelet count, and aspartate aminotransferase, alanine aminotransferase, and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels showed significant differences between the 2 groups, but the C-reactive protein (CRP) levels did not (6.8±3.0 mg/dL vs. 8.3±5.8 mg/dL, P=0.126). In the adenovirus infection group, the CRP levels were <1, <3, <10, and ≥ 10 mg/dL in 2 (5%), 3 (7.5%), 30 (75%), and 5 patients (12.5%), respectively. The cutoff NT-proBNP level was 265 pg/mL. Discrepancy was defined as CRP and NT-proBNP levels of ≥ 3 or <3 mg/dL, and <265 or ≥265 pg/mL, respectively. Among the 35 patients with adenovirus infection whose CRP levels were ≥ 3 mg/dL, 29 (82.9%) showed a discrepancy. Conversely, of the 103 patients with KD whose CRP levels were ≥3 mg/dL, 83 (80.6%) showed no discrepancy. Between the groups, a significant difference in discrepancy rate was observed (P=0.000). None of the patients with adenovirus infection had CRP and NT-proBNP levels of < 3 mg/dL and ≥265 pg/mL, respectively. Conclusion: With a sensitivity of 82.9% and a specificity of 80.6%, CRP and NT-proBNP levels may differentiate between adenoviral PCF and acute KD. © 2018 by The Korean Pediatric Society. | * |
dc.language | English | * |
dc.publisher | Korean Pediatric Society | * |
dc.subject | Adenovirus | * |
dc.subject | C-reactive protein | * |
dc.subject | Discrepancy | * |
dc.subject | Kawasaki disease | * |
dc.subject | NT-proBNP | * |
dc.title | C-reactive protein and N-terminal pro-brain natriuretic peptide discrepancy: A differentiation of adenoviral pharyngoconjunctival fever from Kawasaki disease | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 61 | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 12 | * |
dc.relation.lastpage | 16 | * |
dc.relation.journaltitle | Korean Journal of Pediatrics | * |
dc.identifier.doi | 10.3345/kjp.2018.61.1.12 | * |
dc.identifier.scopusid | 2-s2.0-85040933221 | * |
dc.author.google | Choi J.E. | * |
dc.author.google | Kang H.W. | * |
dc.author.google | Hong Y.M. | * |
dc.author.google | Sohn S. | * |
dc.contributor.scopusid | 홍영미(35210025100;55841904000;56063366100) | * |
dc.contributor.scopusid | 손세정(56577409300) | * |
dc.date.modifydate | 20240415130647 | * |