Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김태헌 | * |
dc.contributor.author | 김성은 | * |
dc.date.accessioned | 2018-02-28T16:30:09Z | - |
dc.date.available | 2018-02-28T16:30:09Z | - |
dc.date.issued | 2019 | * |
dc.identifier.issn | 0192-0790 | * |
dc.identifier.issn | 1539-2031 | * |
dc.identifier.other | OAK-22102 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/240104 | - |
dc.description.abstract | Goals: We aimed to investigate significant factors influencing the long-term prognosis of patients who survived acute-on-chronic liver failure (ACLF). Background: The mortality of ACLF is predominantly affected by the organ failure severity. However, long-term outcomes of patients who survive ACLF are not known. Study: A cohort of 1084 cirrhotic patients who survived for more than 3 months following acute deterioration of liver function was prospectively followed. ACLF was defined by the European Association for the Study of the Liver Chronic Liver Failure Consortium definition. Results: The mean follow-up duration was 19.4 +/- 9.9 months. In the subgroup of patients without previous acute decompensation (AD), ACLF occurrence did not affect long-term outcomes. However, in patients with previous AD, ACLF negatively affected long-term transplant-free survival even after overcoming ACLF (hazard ratio, 2.00, P=0.012). Previous AD was the significant predictive factor of long-term mortality and was independent of the Model for End-stage Liver Disease score in these ACLF-surviving patients. Organ failure severity did not affect transplant-free survival in patients who survived an ACLF episode. Conclusions: A prior history of AD is the most important factor affecting long-term outcomes following an ACLF episode regardless of Model for End-stage Liver Disease score. Prevention of a first AD episode may improve the long-term transplant-free survival of liver cirrhosis patients. | * |
dc.language | English | * |
dc.publisher | LIPPINCOTT WILLIAMS & | * |
dc.publisher | WILKINS | * |
dc.subject | acute-on-chronic liver failure | * |
dc.subject | decompensation | * |
dc.subject | organ failure | * |
dc.subject | survival | * |
dc.title | Long-term Prognosis of Acute-on-Chronic Liver Failure Survivors | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 53 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 134 | * |
dc.relation.lastpage | 141 | * |
dc.relation.journaltitle | JOURNAL OF CLINICAL GASTROENTEROLOGY | * |
dc.identifier.doi | 10.1097/MCG.0000000000000987 | * |
dc.identifier.wosid | WOS:000458415900014 | * |
dc.identifier.scopusid | 2-s2.0-85041627344 | * |
dc.author.google | Yoon, Eileen L. | * |
dc.author.google | Kim, Tae Yeob | * |
dc.author.google | Lee, Chang Hyeong | * |
dc.author.google | Kim, Tae Hun | * |
dc.author.google | Cho, Hyun Chin | * |
dc.author.google | Lee, Sang Soo | * |
dc.author.google | Kim, Sung Eun | * |
dc.author.google | Kim, Hee Yeon | * |
dc.author.google | Kim, Chang Wook | * |
dc.author.google | Song, Do Seon | * |
dc.author.google | Yang, Jin Mo | * |
dc.author.google | Sinn, Dong Hyun | * |
dc.author.google | Jung, Young Kul | * |
dc.author.google | Yim, Hyung Joon | * |
dc.author.google | Kim, Hyoung Su | * |
dc.author.google | Sohn, Joo Hyun | * |
dc.author.google | Kim, Jeong Han | * |
dc.author.google | Choe, Won Hyeok | * |
dc.author.google | Lee, Byung Seok | * |
dc.author.google | Kim, Moon Young | * |
dc.author.google | Jeong, Soung Won | * |
dc.author.google | Choi, Eunhee | * |
dc.author.google | Kim, Dong Joon|Korean Acute-on-Chronic Liver | * |
dc.contributor.scopusid | 김태헌(57125156300;57219781484) | * |
dc.contributor.scopusid | 김성은(35210756100;57204243828) | * |
dc.date.modifydate | 20240422114851 | * |