Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤주영 | * |
dc.date.accessioned | 2017-12-27T16:30:58Z | - |
dc.date.available | 2017-12-27T16:30:58Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0003-2700 | * |
dc.identifier.other | OAK-21455 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/239398 | - |
dc.description.abstract | In this study, the far-red-emitting fluorescence probe 1, containing a rhodamine derivative and a hydrazide reactive group, was developed for peroxynitrite detection and imaging. This probe, which is cell permeable and shows high sensitivity and selectivity in fluorometric detection of peroxynitrite over other ROS/RNS, was successfully utilized to detect exogenous and endogenous peroxynitrite in HeLa and RAW 264.7 cells, respectively. More importantly, 1 can also be used to detect endogenous peroxynitrite generated in Pseudomonas aeruginosa (PAO1)-infected mouse bone marrow-derived neutrophils. We anticipate that the new probe will serve as a powerful molecular imaging tool in investigations of the role(s) played by peroxynitrite in a variety of physiological and pathological contexts. (Figure Presented). © 2017 American Chemical Society. | * |
dc.language | English | * |
dc.publisher | American Chemical Society | * |
dc.title | A Far-Red-Emitting Fluorescence Probe for Sensitive and Selective Detection of Peroxynitrite in Live Cells and Tissues | * |
dc.type | Article | * |
dc.relation.issue | 20 | * |
dc.relation.volume | 89 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 10924 | * |
dc.relation.lastpage | 10931 | * |
dc.relation.journaltitle | Analytical Chemistry | * |
dc.identifier.doi | 10.1021/acs.analchem.7b02707 | * |
dc.identifier.wosid | WOS:000413392500039 | * |
dc.identifier.scopusid | 2-s2.0-85031408435 | * |
dc.author.google | Wu D. | * |
dc.author.google | Ryu J.-C. | * |
dc.author.google | Chung Y.W. | * |
dc.author.google | Lee D. | * |
dc.author.google | Ryu J.-H. | * |
dc.author.google | Yoon J.-H. | * |
dc.author.google | Yoon J. | * |
dc.contributor.scopusid | 윤주영(7403587371) | * |
dc.date.modifydate | 20240118162450 | * |