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Higher body mass index is associated with an increased risk of multiplicity in surveillance colonoscopy within 5 years
- Title
- Higher body mass index is associated with an increased risk of multiplicity in surveillance colonoscopy within 5 years
- Authors
- Tae C.H.; Moon C.M.; Jung S.-A.; Eun C.S.; Park J.J.; Seo G.S.; Cha J.M.; Park S.C.; Chun J.; Lee H.J.; Jung Y.; Kim J.O.; Joo Y.-E.; Boo S.-J.; Il Park D.
- Ewha Authors
- 정성애; 문창모
- SCOPUS Author ID
- 정성애; 문창모
- Issue Date
- 2017
- Journal Title
- Scientific Reports
- ISSN
- 2045-2322
- Citation
- Scientific Reports vol. 7, no. 1
- Publisher
- Nature Publishing Group
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- We aimed to evaluate whether obesity was associated with a certain clinicopathologic characteristics of metachronous CRA. This retrospective longitudinal cohort study included 2,904 subjects who had at least one resected CRA at index colonoscopy and who subsequently underwent one or more surveillance colonoscopies within 5 years. Of the 2,904 subjects, 60.9% (n = 1,769) were normal, 35.8% (n = 1,040) were overweight, and 3.3% (n = 95) were obese. Patients with any metachronous CRA were 53.7% (n = 1,559). In multivariate analyses, higher BMI at index colonoscopy was significantly associated with any metachronous CRA (overweight, OR = 1.07; obese, OR = 1.82; p for trend = 0.049). Regarding the multiplicity, the ORs of ≥ 3, ≥ 4 and ≥ 5 metachronous CRAs significantly increased as index BMI increased (p for trend < 0.001, = 0.007 and = 0.004, respectively). In negative binomial regression regarding the incidence for total number of metachronous CRA, the higher BMI the subject has at the time of index colonoscopy, the more metachronous CRAs the subject will have at the surveillance colonoscopy (p for trend = 0.016). Higher index BMI was significantly associated with the risk of multiple metachronous CRAs on surveillance colonoscopy within 5 years. © 2017 The Author(s).
- DOI
- 10.1038/s41598-017-14163-9
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
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