View : 425 Download: 0

Full metadata record

DC Field Value Language
dc.contributor.author김지은-
dc.date.accessioned2017-10-27T11:45:07Z-
dc.date.available2017-10-27T11:45:07Z-
dc.date.issued2016-
dc.identifier.issn1226-2560-
dc.identifier.issn2093-8144-
dc.identifier.otherOAK-21217-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/237109-
dc.description.abstractAlcohol dependence is a serious disorder that can be related with a number of potential health-related and social consequences. Cortical thickness measurements would provide important information on the cortical structural alterations in patients with alcohol dependence. Twenty-one patients with alcohol dependence and 22 healthy comparison subjects have been recruited and underwent high-resolution brain magnetic resonance (MR) imaging and clinical assessments. T1-weighted MR images were analyzed using the cortical thickness analysis program. Significantly thinner cortical thickness in patients with alcohol dependence than healthy comparison subjects was noted in the left superior frontal cortical region, correcting for multiple comparisons and adjusting with age and hemispheric average cortical thickness. There was a significant association between thickness in the cluster of the left superior frontal cortex and the duration of alcohol use. The prefrontal cortical region may particularly be vulnerable to chronic alcohol exposure. It is also possible that the pre-existing deficit in this region may have rendered individuals more susceptible to alcohol dependence.-
dc.languageEnglish-
dc.publisherKOREAN SOC BRAIN &amp-
dc.publisherNEURAL SCIENCE, KOREAN SOC NEURODEGENERATIVE DISEASE-
dc.subjectAlcoholism-
dc.subjectCerebral Cortex-
dc.subjectFrontal Lobe-
dc.subjectMagnetic Resonance Imaging-
dc.titlePrefrontal Cortical Thickness Deficit in Detoxified Alcohol-dependent Patients-
dc.typeArticle-
dc.relation.issue6-
dc.relation.volume25-
dc.relation.indexKCI-
dc.relation.startpage333-
dc.relation.lastpage341-
dc.relation.journaltitleEXPERIMENTAL NEUROBIOLOGY-
dc.identifier.doi10.5607/en.2016.25.6.333-
dc.identifier.wosidWOS:000406861500006-
dc.author.googleBae, Sujin-
dc.author.googleKang, Ilhyang-
dc.author.googleLee, Boung Chul-
dc.author.googleJeon, Yujin-
dc.author.googleCho, Han Byul-
dc.author.googleYoon, Sujung-
dc.author.googleLim, Soo Mee-
dc.author.googleKim, Jungyoon-
dc.author.googleLyoo, In Kyoon-
dc.author.googleKim, Jieun E.-
dc.author.googleChoi, Ihn-Geun-
dc.contributor.scopusid김지은(55353332200)-
dc.date.modifydate20211117115550-
Appears in Collections:
일반대학원 > 뇌·인지과학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE