Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤여준 | * |
dc.contributor.author | 송명종 | * |
dc.contributor.author | 남상집 | * |
dc.date.accessioned | 2017-08-25T05:08:56Z | - |
dc.date.available | 2017-08-25T05:08:56Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0960-894X | * |
dc.identifier.other | OAK-20774 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/235676 | - |
dc.description.abstract | HPLC-UV guided isolation of the culture broth of a marine bacterium Saccharomonospora sp. CNQ-490 has led to the isolation of two new natural products, lodopyridones B and C (1 and 2) along with the previously reported lodopyridone A (3). Their chemical structures were established from the interpretation of 2D NMR spectroscopic data and the comparison of NMR data with the lodopyridone A (3). Lodopyridones B and C (1 and 2) possess the thiazole, and chloroquinoline groups which are characteristic features of these molecules. Lodopyridones A–C show weak inhibitory activities on the β-site amyloid precursor protein cleaving enzyme 1 (BACE1). © 2017 Elsevier Ltd | * |
dc.language | English | * |
dc.publisher | Elsevier Ltd | * |
dc.subject | BACE1 inhibitor | * |
dc.subject | Lodopyridone | * |
dc.subject | Marine natural products | * |
dc.subject | Saccharomonospora | * |
dc.title | Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp. | * |
dc.type | Article | * |
dc.relation.issue | 14 | * |
dc.relation.volume | 27 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 3123 | * |
dc.relation.lastpage | 3126 | * |
dc.relation.journaltitle | Bioorganic and Medicinal Chemistry Letters | * |
dc.identifier.doi | 10.1016/j.bmcl.2017.05.035 | * |
dc.identifier.wosid | WOS:000404422000017 | * |
dc.identifier.scopusid | 2-s2.0-85019930847 | * |
dc.author.google | Le T.C. | * |
dc.author.google | Yim C.-Y. | * |
dc.author.google | Park S. | * |
dc.author.google | Katila N. | * |
dc.author.google | Yang I. | * |
dc.author.google | Song M.C. | * |
dc.author.google | Yoon Y.J. | * |
dc.author.google | Choi D.-Y. | * |
dc.author.google | Choi H. | * |
dc.author.google | Nam S.-J. | * |
dc.author.google | Fenical W. | * |
dc.contributor.scopusid | 윤여준(7402126465) | * |
dc.contributor.scopusid | 송명종(9335354000) | * |
dc.contributor.scopusid | 남상집(57208839798) | * |
dc.date.modifydate | 20240405124352 | * |