Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김준수 | * |
dc.date.accessioned | 2017-06-13T01:06:09Z | - |
dc.date.available | 2017-06-13T01:06:09Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 2040-3364 | * |
dc.identifier.other | OAK-20706 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/235236 | - |
dc.description.abstract | The first step in the controlled storage of lengthy DNA molecules is to keep DNA molecules separated while integrated in micrometer-sized space. Herein, we present hybrid Monte Carlo simulations of a histone-complexed DNA (hcDNA) molecule confined in a dense array of nanoposts. Depending on the nanopost dimension, a single, 8.7 kilobase pair hcDNA molecule was either localized and elongated in a single inter-post space surrounded by four nanoposts or spread over several inter-post spaces through passages between two neighboring nanoposts. The conformational change of a hcDNA molecule is interpreted in terms of competitive effects of confinements in the inter-post and passage spaces. We propose that, by elaborately designing nanopost arrays, the competitive confinement effects can be adjusted such that each hcDNA molecule is localized in a single inter-post space, and thereby multiple hcDNA molecules can be physically separated from each other while stored together in the nanopost array. © 2017 The Royal Society of Chemistry. | * |
dc.language | English | * |
dc.publisher | Royal Society of Chemistry | * |
dc.title | Confinement-driven organization of a histone-complexed DNA molecule in a dense array of nanoposts | * |
dc.type | Article | * |
dc.relation.issue | 19 | * |
dc.relation.volume | 9 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 6391 | * |
dc.relation.lastpage | 6398 | * |
dc.relation.journaltitle | Nanoscale | * |
dc.identifier.doi | 10.1039/c7nr00859g | * |
dc.identifier.wosid | WOS:000401649700021 | * |
dc.identifier.scopusid | 2-s2.0-85021787698 | * |
dc.author.google | Joo H. | * |
dc.author.google | Kim J.S. | * |
dc.contributor.scopusid | 김준수(23670121600) | * |
dc.date.modifydate | 20240215165024 | * |