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dc.contributor.author김수정-
dc.date.accessioned2017-02-15T08:02:58Z-
dc.date.available2017-02-15T08:02:58Z-
dc.date.issued2017-
dc.identifier.issn1471-2466-
dc.identifier.otherOAK-20055-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/234486-
dc.description.abstractBackground: Patients with distinctive morphotype were more susceptible to nontuberculous mycobacterial lung disease (NTM-LD). However, little is known about the association between body morphotype and progression of NTM-LD. The aim of this study was to elucidate predictors of NTM-LD progression, focusing on body morphotype and composition. Methods: Data from patients with NTM-LD who participated in NTM cohort which started in 1 July 2011 were analyzed. Patients with more than 6 months of follow up were included for analysis. NTM-LD progression was defined as clinicianinitiated anti-NTM treatment, based on symptomatic and radiologic aggravation. Body morphotype and composition was measured at entry to the cohort using bioelectrical impedance analysis. Results: NTM-LD progressed in 47 out of 150 patients with more than 6 months of follow up. Patients with middle (adjusted hazard ratio [aHR], 2.758; 95% confidence interval [CI], 1.112-6.843) or lowest tertile (aHR, 3.084; 95% CI, 1.241-7. 668) of abdominal fat ratio had a higher risk of disease progression compared with the highest tertile. Other predictors for disease progression were presence of cavity on chest computed tomography (aHR, 4.577; 95% CI, 2.364-8.861), and serum albumin level < 3.5 g/dL (aHR, 12.943; 95% CI, 2.588-64.718). Conclusions: Progression of NTM-LD is associated with body composition. Lower abdominal fat ratio is an independent predictor of NTM-LD progression.-
dc.languageEnglish-
dc.publisherBIOMED CENTRAL LTD-
dc.subjectAbdominal fat-
dc.subjectAnthropometry-
dc.subjectBody composition-
dc.subjectNontuberculous mycobacteria-
dc.titleCharacteristics associated with progression in patients with of nontuberculous mycobacterial lung disease : a prospective cohort study-
dc.typeArticle-
dc.relation.volume17-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.journaltitleBMC PULMONARY MEDICINE-
dc.identifier.doi10.1186/s12890-016-0349-3-
dc.identifier.wosidWOS:000391893300004-
dc.identifier.scopusid2-s2.0-85008323146-
dc.author.googleKim, Soo Jung-
dc.author.googleYoon, Soon Ho-
dc.author.googleChoi, Sun Mi-
dc.author.googleLee, Jinwoo-
dc.author.googleLee, Chang-Hoon-
dc.author.googleHan, Sung Koo-
dc.author.googleYim, Jae-Joon-
dc.contributor.scopusid김수정(57203772978;57218161842)-
dc.date.modifydate20220329104030-


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