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DSpace at EWHA약학대학 약학과 Journal papers

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Synthesis and antitumor activity of fluorocyclopentenyl-pyrimidines

Title: Synthesis and antitumor activity of fluorocyclopentenyl-pyrimidines

Authors: Jeong L.S.; Zhao L.X.; Choi W.J.; Pal S.; Park Y.H.; Lee S.K.; Chun M.W.; Lee Y.B.; Ahn C.H.; Moon H.R.

Ewha Authors: 정낙신; 이상국

SCOPUS Author ID: 정낙신; 이상국

Issue Date: 2007

Journal Title: Nucleosides, Nucleotides and Nucleic Acids

ISSN: 1525-7770

Citation: Nucleosides, Nucleotides and Nucleic Acids vol. 26, no. 41432, pp. 713 - 716

Indexed: SCIE; SCOPUS

Document Type: Conference Paper

Abstract: Synthesis of fluorocyclopentenyl pyrimidine nucleosides 6-9 was enantiopurely accomplished employing oxidative rearrangement, RCM reaction and electrophilic fluorination starting from D-ribose. Cytosine analog 8 was found to exhibit significant anticancer activity in various human tumor cell lines. Copyright © Taylor & Francis Group, LLC.

DOI: 10.1080/15257770701490852

Appears in Collections:: 약학대학 > 약학과 > Journal papers

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