Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정낙신 | - |
dc.date.accessioned | 2017-01-18T02:01:25Z | - |
dc.date.available | 2017-01-18T02:01:25Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 1525-7770 | - |
dc.identifier.other | OAK-4497 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/233911 | - |
dc.description.abstract | Apio fluoroneplanocin A (apio F-NPA, 3) and its uracil analogue 4 have been designed and asymmetrically synthesized starting from D-ribose. Introduction of fluoro group into vinylic position of 5 was accomplished successfully over 5 steps employing key reactions such as iodination according to an addition-elimination reaction mechanism, stereo- and regioselective reduction of α,β -unsaturated ketone, and electrophilic fluorination. This methodology can be adapted to the synthesis of fluoro compounds extensively. Copyright © Taylor & Francis Group, LLC. | - |
dc.language | English | - |
dc.title | Asymmetric synthesis of apio fluoroneplanocin a analogs as potential AdoHcy hydrolase inhibitor | - |
dc.type | Article | - |
dc.relation.issue | 41495 | - |
dc.relation.volume | 26 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 943 | - |
dc.relation.lastpage | 947 | - |
dc.relation.journaltitle | Nucleosides, Nucleotides and Nucleic Acids | - |
dc.identifier.doi | 10.1080/15257770701508000 | - |
dc.identifier.wosid | WOS:000251875400017 | - |
dc.identifier.scopusid | 2-s2.0-36849023026 | - |
dc.author.google | Park A.-Y. | - |
dc.author.google | Moon H.R. | - |
dc.author.google | Kim K.R. | - |
dc.author.google | Kang J.-A. | - |
dc.author.google | Chun M.W. | - |
dc.author.google | Jeong L.S. | - |
dc.contributor.scopusid | 정낙신(16028528200) | - |
dc.date.modifydate | 20211210153610 | - |