Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김화영 | * |
dc.contributor.author | 정혜원 | * |
dc.date.accessioned | 2016-12-06T02:12:24Z | - |
dc.date.available | 2016-12-06T02:12:24Z | - |
dc.date.issued | 2008 | * |
dc.identifier.issn | 0250-6807 | * |
dc.identifier.other | OAK-5046 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/233008 | - |
dc.description.abstract | Aims: This study was conducted to determine the antioxidant capacity, immunomodulatory and lipid-lowering effects of spirulina in healthy elderly subjects and to document the effectiveness of spirulina as a functional food for the elderly. Methods: A randomized double-blind, placebo-controlled study was performed. The subjects were 78 individuals aged 60-87 years and were randomly assigned in a blinded fashion to receive either spirulina or placebo. The elderly were instructed to consume the spirulina or placebo at home, 8 g/day, for 16 consecutive weeks. Results: In male subjects, a significant plasma cholesterol-lowering effect was observed after the spirulina intervention (p < 0.05). Spirulina supplementation resulted in a significant rise in plasma interleukin (IL)-2 concentration, and a significant reduction in IL-6 concentration. A significant time-by-treatment intervention for total antioxidant status was observed between spirulina and placebo groups (p < 0.05). In female subjects, significant increases in IL-2 level and superoxide dismutase activity were observed (p < 0.05) after spirulina supplementation. There were significant reductions in total cholesterol in female subjects. Conclusions: The results demonstrate that spirulina has favorable effects on lipid profiles, immune variables, and antioxidant capacity in healthy, elderly male and female subjects and is suitable as a functional food. Copyright © 2008 S. Karger AG. | * |
dc.language | English | * |
dc.title | A randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 52 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 322 | * |
dc.relation.lastpage | 328 | * |
dc.relation.journaltitle | Annals of Nutrition and Metabolism | * |
dc.identifier.doi | 10.1159/000151486 | * |
dc.identifier.wosid | WOS:000259032200010 | * |
dc.identifier.scopusid | 2-s2.0-49549089757 | * |
dc.author.google | Park H.J. | * |
dc.author.google | Lee Y.J. | * |
dc.author.google | Ryu H.K. | * |
dc.author.google | Kim M.H. | * |
dc.author.google | Chung H.W. | * |
dc.author.google | Kim W.Y. | * |
dc.contributor.scopusid | 김화영(35201071000;57213043374) | * |
dc.contributor.scopusid | 정혜원(56499737200) | * |
dc.date.modifydate | 20240415131357 | * |