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dc.contributor.author김화영-
dc.contributor.author정혜원-
dc.date.accessioned2016-12-06T02:12:24Z-
dc.date.available2016-12-06T02:12:24Z-
dc.date.issued2008-
dc.identifier.issn0250-6807-
dc.identifier.otherOAK-5046-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/233008-
dc.description.abstractAims: This study was conducted to determine the antioxidant capacity, immunomodulatory and lipid-lowering effects of spirulina in healthy elderly subjects and to document the effectiveness of spirulina as a functional food for the elderly. Methods: A randomized double-blind, placebo-controlled study was performed. The subjects were 78 individuals aged 60-87 years and were randomly assigned in a blinded fashion to receive either spirulina or placebo. The elderly were instructed to consume the spirulina or placebo at home, 8 g/day, for 16 consecutive weeks. Results: In male subjects, a significant plasma cholesterol-lowering effect was observed after the spirulina intervention (p < 0.05). Spirulina supplementation resulted in a significant rise in plasma interleukin (IL)-2 concentration, and a significant reduction in IL-6 concentration. A significant time-by-treatment intervention for total antioxidant status was observed between spirulina and placebo groups (p < 0.05). In female subjects, significant increases in IL-2 level and superoxide dismutase activity were observed (p < 0.05) after spirulina supplementation. There were significant reductions in total cholesterol in female subjects. Conclusions: The results demonstrate that spirulina has favorable effects on lipid profiles, immune variables, and antioxidant capacity in healthy, elderly male and female subjects and is suitable as a functional food. Copyright © 2008 S. Karger AG.-
dc.languageEnglish-
dc.titleA randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly Koreans-
dc.typeArticle-
dc.relation.issue4-
dc.relation.volume52-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage322-
dc.relation.lastpage328-
dc.relation.journaltitleAnnals of Nutrition and Metabolism-
dc.identifier.doi10.1159/000151486-
dc.identifier.wosidWOS:000259032200010-
dc.identifier.scopusid2-s2.0-49549089757-
dc.author.googlePark H.J.-
dc.author.googleLee Y.J.-
dc.author.googleRyu H.K.-
dc.author.googleKim M.H.-
dc.author.googleChung H.W.-
dc.author.googleKim W.Y.-
dc.contributor.scopusid김화영(35201071000)-
dc.contributor.scopusid정혜원(56499737200)-
dc.date.modifydate20180329110413-
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신산업융합대학 > 식품영양학과 > Journal papers
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