Chirality conversion and enantioselective extraction of amino acids by imidazolium-based binol-aldehyde

Abstract

A novel imidazolium-based binol receptor 4 has been synthesized and used as a chirality conversion reagent for general amino acids with higher d-form selectivity compared to other guanidinium-based receptors. Favorable solubility in chloroform enabled 4 as an effective chiral extractant for the resolution of racemic amino acids. © 2008 Elsevier Ltd. All rights reserved.