Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 황금숙 | * |
dc.date.accessioned | 2016-08-29T12:08:03Z | - |
dc.date.available | 2016-08-29T12:08:03Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0003-2670 | * |
dc.identifier.issn | 1873-4324 | * |
dc.identifier.other | OAK-19021 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/231722 | - |
dc.description.abstract | The goal of metabolomics is to analyze a whole metabolome under a given set of conditions, and accurate and reliable quantitation of metabolites is crucial. Absolute concentration is more valuable than relative concentration; however, the most commonly used method in NMR-based serum metabolic profiling, bin-based and full data point peak quantification, provides relative concentration levels of metabolites and are not reliable when metabolite peaks overlap in a spectrum. In this study, we present the software-assisted serum metabolite quantification (SASMeQ) method, which allows us to identify and quantify metabolites in NMR spectra using Chenomx software. This software uses the ERETIC2 utility from TopSpin to add a digitally synthesized peak to a spectrum. The SASMeQ method will advance NMR-based serum metabolic profiling by providing an accurate and reliable method for absolute quantification that is superior to bin-based quantification. (C) 2016 Elsevier B.V. All rights reserved. | * |
dc.language | English | * |
dc.publisher | ELSEVIER SCIENCE BV | * |
dc.subject | Metabolomics | * |
dc.subject | Nuclear magnetic resonance | * |
dc.subject | Serum | * |
dc.subject | Quantification | * |
dc.subject | Profiling | * |
dc.title | Software-assisted serum metabolite quantification using NMR | * |
dc.type | Article | * |
dc.relation.volume | 934 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 194 | * |
dc.relation.lastpage | 202 | * |
dc.relation.journaltitle | ANALYTICA CHIMICA ACTA | * |
dc.identifier.doi | 10.1016/j.aca.2016.04.054 | * |
dc.identifier.wosid | WOS:000381928900023 | * |
dc.identifier.scopusid | 2-s2.0-84977609943 | * |
dc.author.google | Jung, Young-Sang | * |
dc.author.google | Hyeon, Jin-Seong | * |
dc.author.google | Hwang, Geum-Sook | * |
dc.contributor.scopusid | 황금숙(7202676099) | * |
dc.date.modifydate | 20240222154747 | * |