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Actinobenzoquinoline and Actinophenanthrolines A-C, Unprecedented Alkaloids from a Marine Actinobacterium

Title
Actinobenzoquinoline and Actinophenanthrolines A-C, Unprecedented Alkaloids from a Marine Actinobacterium
Authors
Nam, Sang-JipKauffman, Christopher A.Jensen, Paul R.Moore, Curtis E.Rheingold, Arnold L.Fenical, William
Ewha Authors
남상집
SCOPUS Author ID
남상집scopusscopus
Issue Date
2015
Journal Title
ORGANIC LETTERS
ISSN
1523-7060JCR Link

1523-7052JCR Link
Citation
ORGANIC LETTERS vol. 17, no. 13, pp. 3240 - 3243
Publisher
AMER CHEMICAL SOC
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Chemical investigation of a marine actinomycete within the family Streptomycetaceae (our strain CNQ-149) has led to the isolation of the unprecedented alkaloids, actinobenzoquinoline (1) and actinophenanthrolines A-C (2-4). The chemical structures of 1-4 were assigned by interpretation of NMR spectroscopic data, and their absolute configurations were assigned by X-ray analysis. Actinobenzoquinoline possesses a 5-methyloxazolidin-4-one moiety and a dihydrobento[h],quinoline core structure, while actinophenanthrolines A-C are composed of hydroxypropanamide-substituted 1,7-phenanthroline core skeletons.
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DOI
10.1021/acs.orglett.5b01387
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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