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Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism

Title
Effects of a Dietary Supplement with Barley Sprout Extract on Blood Cholesterol Metabolism
Authors
Byun A.R.Chun H.Lee J.Lee S.W.Lee H.S.Shim K.W.
Ewha Authors
이상화이홍수심경원전혜진
SCOPUS Author ID
이상화scopusscopus; 이홍수scopus; 심경원scopus; 전혜진scopus
Issue Date
2015
Journal Title
Evidence-based Complementary and Alternative Medicine
ISSN
1741-427XJCR Link
Citation
Evidence-based Complementary and Alternative Medicine vol. 2015
Publisher
Hindawi Publishing Corporation
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Objective. Barley sprout (Hordeum vulgare L.) contains 4.97% fat, 52.6% polysaccharide, and 34.1% protein along with a variety of vitamins, minerals, and polyphenolic compounds. Hexacosanol is one such compound from the barley leaf that might improve cholesterol metabolism by decreasing cholesterol synthesis. Method. Therefore, this study was conducted to investigate the effects of barley sprout extract on serum lipid metabolism in healthy volunteers (n = 51). Subjects were randomly divided into two groups: one group consumed a single capsule of barley leaf extract daily (n = 25, 42.48 ± 13.58 years) and the other consumed placebo capsules (n = 26, 40.54 ± 11.1 years) for 12 weeks. Results. After 12 weeks, total cholesterol and low-density lipoprotein- (LDL-) cholesterol were not lower in the barley sprout extract group compared to the placebo group (p = 0.415 and p = 0.351, resp.) and no differences in clinical or laboratory findings were observed between both groups. Conclusion. Our study failed to show significant lipid-lowering effects of barley sprout extract, possibly due to dosage, duration of therapy, and small sample size. Despite our nonsignificant findings, barley sprout has a possibility as a functional health food; therefore future research is needed. © 2015 A Ri Byun et al.
DOI
10.1155/2015/473056
Appears in Collections:
의과대학 > 의학과 > Journal papers
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