Association of gene polymorphisms with the risk of warfarin bleeding complications at therapeutic INR in patients with mechanical cardiac valves

Abstract

bleeding; C-reactive protein (CRP); cytochrome P450 subfamily 2C polypeptide 9 (CYP2C9); genotype; international normalized ratio (INR); thrombomodulin (THBD); vitamin K epoxide reductase complex subunit 1 (VKORC1); warfarin