Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 이진화 | * |
dc.date.accessioned | 2016-08-28T10:08:17Z | - |
dc.date.available | 2016-08-28T10:08:17Z | - |
dc.date.issued | 2013 | * |
dc.identifier.issn | 0341-2040 | * |
dc.identifier.other | OAK-10300 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223904 | - |
dc.description.abstract | Background: The progression of lung hyperinflation in patients with chronic obstructive pulmonary disease (COPD) has not been studied in a long-term prospective cohort. We explored the longitudinal changes in lung volume compartments with the aim of identifying predictors of a rapid decline of the inspiratory capacity to total lung capacity ratio (IC/TLC). Methods: The study population comprised 324 patients with COPD who were recruited prospectively. Annual rates of changes in pulmonary function, including forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), vital capacity (VC), IC, and IC/TLC, were estimated using the random coefficient models. Results: The mean annual rates of changes in pre- and post-bronchodilator FEV1 were -23.0 mL/year (p < 0.001) and -26.5 mL/year (p = 0.004). The mean annual rates of changes in VC, IC, TLC, and IC/TLC were -33.7 mL/year (p = 0.007), -53.9 mL/year (p < 0.001), -43.7 mL/year (p = 0.012), and -0.65 %/year (p = 0.001), respectively. RV, FRC, and RV/TLC did not change significantly during the study period. Multivariate logistic regression analysis showed that a high modified Medical Research Council (MMRC) dyspnea scale score, a high Charlson comorbidity index value, and low post-bronchodilator FEV1 were associated with rapid decline in IC/TLC. Conclusion: MMRC dyspnea scale, post-bronchodilator FEV1, and the Charlson comorbidity index at baseline were independent predictors of a rapid decline in IC/TLC. © 2013 Springer Science+Business Media New York. | * |
dc.language | English | * |
dc.title | Longitudinal lung volume changes in patients with chronic obstructive pulmonary disease | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 191 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 405 | * |
dc.relation.lastpage | 412 | * |
dc.relation.journaltitle | Lung | * |
dc.identifier.doi | 10.1007/s00408-013-9478-0 | * |
dc.identifier.wosid | WOS:000321916800013 | * |
dc.identifier.scopusid | 2-s2.0-84880828247 | * |
dc.author.google | Lee J.S. | * |
dc.author.google | Kim S.O. | * |
dc.author.google | Seo J.B. | * |
dc.author.google | Lee J.-H. | * |
dc.author.google | Kim E.K. | * |
dc.author.google | Kim T.-H. | * |
dc.author.google | Kim W.J. | * |
dc.author.google | Lee J.H. | * |
dc.author.google | Lee S.-M. | * |
dc.author.google | Lee S. | * |
dc.author.google | Lim S.Y. | * |
dc.author.google | Shin T.R. | * |
dc.author.google | Yoon H.I. | * |
dc.author.google | Lee S.W. | * |
dc.author.google | Huh J.W. | * |
dc.author.google | Oh Y.-M. | * |
dc.author.google | Lee S.-D. | * |
dc.contributor.scopusid | 이진화(56646645800;58376333800) | * |
dc.date.modifydate | 20240419140935 | * |