Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 조영주 | * |
dc.date.accessioned | 2016-08-28T10:08:23Z | - |
dc.date.available | 2016-08-28T10:08:23Z | - |
dc.date.issued | 2013 | * |
dc.identifier.issn | 0954-6111 | * |
dc.identifier.other | OAK-9719 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223396 | - |
dc.description.abstract | Background: Aspirin-intolerant asthma is a unique clinical syndrome characterized by acute bronchoconstriction following the administration of aspirin and/or non-steroidal anti-inflammatory drugs. Objective: We assessed the prevalence and investigated the demographic and clinical characteristics of adult patients with aspirin-intolerant asthma in Korea. Methods: Using an adult asthma cohort (COREA) from 11 university hospitals in Korea, we analyzed the prevalence of aspirin-intolerant asthma, defined as a positive response to the question: "Have you ever experienced dyspnea and cough after taking an aspirin or any NSAID (cold medicine)?" Demographic and clinical characteristics were compared between patients with aspirin-intolerant asthma and aspirin-tolerant asthma. Results: Aspirin-intolerant asthma was reported in 68 (5.8%) of 1173 adult asthmatics (age 15-84). Patients with aspirin-intolerant asthma had a lower mean age (43.9 ± 13.4 vs. 49.0 ± 15.6, P = 0.003) and a higher prevalence of rhinosinusitis (77.9% vs. 61.7%, P = 0.012) and atopic dermatitis (16.2% vs. 5.7%, P = 0.001) than aspirin-tolerant asthma patients. There were no significant differences in lung function, asthma severity or the use of asthma controllers. However, aspirin-intolerant asthma was associated with greater use of healthcare services over a lifetime and over the past 12 months. Aspirin-intolerant asthma was significantly associated with emergency room visits over the past 12 months (P = 0.029, OR 2.19, 95% CI 1.08-4.42). Conclusion: Based on histories, the prevalence of aspirin-intolerant asthma is 5.8% among adult asthma patients in Korea. Aspirin-intolerant asthma is associated with lower age, higher prevalence of rhinosinusitis and atopic dermatitis, and more frequent exacerbations.© 2012 Elsevier Ltd. All rights reserved. | * |
dc.language | English | * |
dc.title | Aspirin-intolerant asthma in the Korean population: Prevalence and characteristics based on a questionnaire survey | * |
dc.type | Review | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 107 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 202 | * |
dc.relation.lastpage | 208 | * |
dc.relation.journaltitle | Respiratory Medicine | * |
dc.identifier.doi | 10.1016/j.rmed.2012.10.020 | * |
dc.identifier.wosid | WOS:000314556000005 | * |
dc.identifier.scopusid | 2-s2.0-84872120319 | * |
dc.author.google | Moon J.-Y. | * |
dc.author.google | Kim S.-H. | * |
dc.author.google | Kim T.-B. | * |
dc.author.google | Chang Y.-S. | * |
dc.author.google | Lee J.H. | * |
dc.author.google | Cho Y.S. | * |
dc.author.google | Park J.W. | * |
dc.author.google | Jang A.-S. | * |
dc.author.google | Park C.-S. | * |
dc.author.google | Nahm D.-H. | * |
dc.author.google | Cho Y.-J. | * |
dc.author.google | Cho S.-H. | * |
dc.author.google | Choi B.-W. | * |
dc.author.google | Moon H.-B. | * |
dc.author.google | Yoon H.J. | * |
dc.contributor.scopusid | 조영주(55472202600;56657140200) | * |
dc.date.modifydate | 20240118125203 | * |