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dc.contributor.author김동하-
dc.date.accessioned2016-08-28T10:08:10Z-
dc.date.available2016-08-28T10:08:10Z-
dc.date.issued2012-
dc.identifier.issn0003-6951-
dc.identifier.otherOAK-9553-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/223262-
dc.description.abstractWe have performed highly sensitive surface plasmon resonance (SPR) detection by colocalizing the evanescent near-fields and target molecular distribution. The colocalization is based on oblique metal evaporation to form nanogaps of a size under 100 nm without using electron-beam lithography. The concept was demonstrated by detecting siloxane-based biotin/streptavidin interactions. 50-nm nanogaps produced the largest amplification of optical signatures and two orders of magnitude enhancement of sensitivity over conventional thin film-based measurements. The enhancement is associated with efficient overlap of localized near-fields and target. Colocalized detection scheme is expected to provide clues to molecular sensitivity for SPR biosensing. © 2012 American Institute of Physics.-
dc.languageEnglish-
dc.titleNanogap-based dielectric-specific colocalization for highly sensitive surface plasmon resonance detection of biotin-streptavidin interactions-
dc.typeArticle-
dc.relation.issue23-
dc.relation.volume101-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.journaltitleApplied Physics Letters-
dc.identifier.doi10.1063/1.4769108-
dc.identifier.wosidWOS:000312243900092-
dc.identifier.scopusid2-s2.0-84870921657-
dc.author.googleKim Y.-
dc.author.googleChung K.-
dc.author.googleLee W.-
dc.author.googleHa Kim D.-
dc.author.googleKim D.-
dc.contributor.scopusid김동하(26039227400)-
dc.date.modifydate20210708161835-


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