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Heterologous production of 4- O -demethylbarbamide, a marine cyanobacterial natural product

Title
Heterologous production of 4- O -demethylbarbamide, a marine cyanobacterial natural product
Authors
Kim E.J.Lee J.H.Choi H.Pereira A.R.Ban Y.H.Yoo Y.J.Kim E.Park J.W.Sherman D.H.Gerwick W.H.Yoon Y.J.
Ewha Authors
윤여준
SCOPUS Author ID
윤여준scopus
Issue Date
2012
Journal Title
Organic Letters
ISSN
1523-7060JCR Link
Citation
Organic Letters vol. 14, no. 23, pp. 5824 - 5827
Indexed
SCI; SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Heterologous expression of the barbamide biosynthetic gene cluster, obtained from the marine cyanobacterium Moorea producens, in the terrestrial actinobacterium Streptomyces venezuelae, resulted in the production of a new barbamide congener 4-O-demethylbarbamide, demonstrating the potential of this approach for investigating the assembly and tailoring of complex marine natural products. © 2012 American Chemical Society.
DOI
10.1021/ol302575h
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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