Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정낙신 | - |
dc.date.accessioned | 2016-08-28T10:08:49Z | - |
dc.date.available | 2016-08-28T10:08:49Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.other | OAK-9257 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/223044 | - |
dc.description.abstract | K-7174, a GATA-specific inhibitor, is a putative anti-inflammatory agent that attenuates effects of inflammatory cytokines in certain cell types. An expeditious four-step synthesis of K-7174 is described in this paper. The route employs Wittig olefination and bis-alkylation of homopiperazine as the key reactions. The iodinecatalyzed isomerization of the Z-isomer results in complete conversion to the E-isomer is the highlight of our synthetic endeavors. | - |
dc.language | English | - |
dc.title | A straightforward synthesis of K-7174, a GATA-specific inhibitor | - |
dc.type | Article | - |
dc.relation.issue | 9 | - |
dc.relation.volume | 33 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 2903 | - |
dc.relation.lastpage | 2906 | - |
dc.relation.journaltitle | Bulletin of the Korean Chemical Society | - |
dc.identifier.doi | 10.5012/bkcs.2012.33.9.2903 | - |
dc.identifier.wosid | WOS:000309307400015 | - |
dc.identifier.scopusid | 2-s2.0-84866405816 | - |
dc.author.google | Majik M.S. | - |
dc.author.google | Yu J.H. | - |
dc.author.google | Jeong L.S. | - |
dc.contributor.scopusid | 정낙신(16028528200) | - |
dc.date.modifydate | 20211210153610 | - |