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dc.contributor.author황승균-
dc.date.accessioned2016-08-28T10:08:42Z-
dc.date.available2016-08-28T10:08:42Z-
dc.date.issued2012-
dc.identifier.issn1011-8934-
dc.identifier.otherOAK-9166-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/222972-
dc.description.abstractThe authors performed a multicenter prospective study to evaluate the feasibility and safety of intravenous nicardipine hydrochloride for acute hypertension in patients with intracerebral hemorrhage (ICH). This study included 88 patients (mean age: 58.3 yr, range 26-87 yr) with ICH and acute hypertension in 5 medical centers between August 2008 and November 2010, who were treated using intravenous nicardipine. Administration of nicardipine resulted in a decrease from mean systolic blood pressure (BP) (175.4 ± 33.7 mmHg) and diastolic BP (100.8 ± 22 mmHg) at admission to mean systolic BP (127.4 ± 16.7 mmHg) and diastolic BP (67.2 ± 12.9 mmHg) in 6 hr after infusion (P < 0.001, mixed-effect linear models). Among patients who underwent follow-up by computed tomography, hematoma expansion at 24 hr (more than 33% increase in hematoma size at 24 hr) was observed in 3 (3.4%) of 88 patients. Neurological deterioration (defined as a decrease in initial Glasgow coma scale ≥ 2) was observed in 2 (2.2%) of 88 patients during the treatment. Aggressive nicardipine treatment of acute hypertension in patients with ICH can be safe and effective with a low rate of neurological deterioration and hematoma expansion. © 2012 The Korean Academy of Medical Sciences.-
dc.languageEnglish-
dc.titleAntihypertensive treatment of acute intracerebral hemorrhage by intravenous nicardipine hydrochloride: Prospective multi-center study-
dc.typeArticle-
dc.relation.issue9-
dc.relation.volume27-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage1085-
dc.relation.lastpage1090-
dc.relation.journaltitleJournal of Korean Medical Science-
dc.identifier.doi10.3346/jkms.2012.27.9.1085-
dc.identifier.wosidWOS:000308303000018-
dc.identifier.scopusid2-s2.0-84866397323-
dc.author.googleHwang S.-K.-
dc.author.googleKim J.-S.-
dc.author.googleKim J.H.-
dc.author.googleHong C.-K.-
dc.author.googleYang K.H.-
dc.contributor.scopusid황승균(35187436400)-
dc.date.modifydate20180329110934-
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의과대학 > 의학과 > Journal papers
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