Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 황승균 | - |
dc.date.accessioned | 2016-08-28T10:08:42Z | - |
dc.date.available | 2016-08-28T10:08:42Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.other | OAK-9166 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/222972 | - |
dc.description.abstract | The authors performed a multicenter prospective study to evaluate the feasibility and safety of intravenous nicardipine hydrochloride for acute hypertension in patients with intracerebral hemorrhage (ICH). This study included 88 patients (mean age: 58.3 yr, range 26-87 yr) with ICH and acute hypertension in 5 medical centers between August 2008 and November 2010, who were treated using intravenous nicardipine. Administration of nicardipine resulted in a decrease from mean systolic blood pressure (BP) (175.4 ± 33.7 mmHg) and diastolic BP (100.8 ± 22 mmHg) at admission to mean systolic BP (127.4 ± 16.7 mmHg) and diastolic BP (67.2 ± 12.9 mmHg) in 6 hr after infusion (P < 0.001, mixed-effect linear models). Among patients who underwent follow-up by computed tomography, hematoma expansion at 24 hr (more than 33% increase in hematoma size at 24 hr) was observed in 3 (3.4%) of 88 patients. Neurological deterioration (defined as a decrease in initial Glasgow coma scale ≥ 2) was observed in 2 (2.2%) of 88 patients during the treatment. Aggressive nicardipine treatment of acute hypertension in patients with ICH can be safe and effective with a low rate of neurological deterioration and hematoma expansion. © 2012 The Korean Academy of Medical Sciences. | - |
dc.language | English | - |
dc.title | Antihypertensive treatment of acute intracerebral hemorrhage by intravenous nicardipine hydrochloride: Prospective multi-center study | - |
dc.type | Article | - |
dc.relation.issue | 9 | - |
dc.relation.volume | 27 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 1085 | - |
dc.relation.lastpage | 1090 | - |
dc.relation.journaltitle | Journal of Korean Medical Science | - |
dc.identifier.doi | 10.3346/jkms.2012.27.9.1085 | - |
dc.identifier.wosid | WOS:000308303000018 | - |
dc.identifier.scopusid | 2-s2.0-84866397323 | - |
dc.author.google | Hwang S.-K. | - |
dc.author.google | Kim J.-S. | - |
dc.author.google | Kim J.H. | - |
dc.author.google | Hong C.-K. | - |
dc.author.google | Yang K.H. | - |
dc.contributor.scopusid | 황승균(35187436400) | - |
dc.date.modifydate | 20180329110934 | - |