Recognition of myo-inositol 1,4,5-trisphosphate using a fluorescent imidazolium receptor

Abstract

The first example of an imidazolium-based fluorescent receptor for d-myo-inositol 1,4,5-trisphosphate (IP 3) is reported in this study. The fluorescent receptor 1 bearing four imidazolium and pyrene groups displayed a large fluorescent quenching effect with myo-IP 3 compared to fluorescent changes with various IP series, pyrophosphate, and ATP. © 2012 The Royal Society of Chemistry.