Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이병구 | - |
dc.date.accessioned | 2016-08-28T12:08:35Z | - |
dc.date.available | 2016-08-28T12:08:35Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0367-326X | - |
dc.identifier.other | OAK-6812 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220987 | - |
dc.description.abstract | The effects of scoparone on dopamine release in PC12 cells were investigated. Scoparone at 50-200 μM increased dopamine release into the culture medium. However, the released levels of dopamine by scoparone were not altered in the absence of extracellular Ca 2+ and by adenylyl cyclase inhibitor MDL-12,330A. Scoparone increased phosphorylation of PKA, CaMK II and synapsin I. Scoparone also enhanced K +-induced levels of dopamine release by CaMK II phosphorylation. These results suggest that scoparone increases dopamine release by synapsin I phosphorylation via activation of PKA and CaMK II, which are mediated by cyclic AMP levels and Ca 2+ influx. © 2010 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.title | Effects of scoparone on dopamine release in PC12 cells | - |
dc.type | Article | - |
dc.relation.issue | 6 | - |
dc.relation.volume | 81 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 497 | - |
dc.relation.lastpage | 502 | - |
dc.relation.journaltitle | Fitoterapia | - |
dc.identifier.doi | 10.1016/j.fitote.2010.01.003 | - |
dc.identifier.wosid | WOS:000281073800008 | - |
dc.identifier.scopusid | 2-s2.0-77955709043 | - |
dc.author.google | Yang Y.J. | - |
dc.author.google | Lee H.J. | - |
dc.author.google | Lee B.K. | - |
dc.author.google | Lim S.C. | - |
dc.author.google | Lee C.K. | - |
dc.author.google | Lee M.K. | - |
dc.contributor.scopusid | 이병구(55502906900;55758384300) | - |
dc.date.modifydate | 20220119161839 | - |