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dc.contributor.author박혜영-
dc.date.accessioned2016-08-28T12:08:33Z-
dc.date.available2016-08-28T12:08:33Z-
dc.date.issued2010-
dc.identifier.issn0968-0896-
dc.identifier.otherOAK-6788-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/220965-
dc.description.abstractNovel diphenylpiperazine derivatives were synthesized and evaluated for their inhibitory activity against T-type calcium channel by whole-cell patch clamp recordings on HEK293 cells. Among the test compounds, 2 and 3d were effective in decreasing the response to formalin in both the first and second phases and demonstrated antiallodynic effects in a rat model of neuropathic pain. © 2010 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.titleSynthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activity-
dc.typeArticle-
dc.relation.issue16-
dc.relation.volume18-
dc.relation.indexSCI-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage5938-
dc.relation.lastpage5944-
dc.relation.journaltitleBioorganic and Medicinal Chemistry-
dc.identifier.doi10.1016/j.bmc.2010.06.082-
dc.identifier.wosidWOS:000280664100017-
dc.identifier.scopusid2-s2.0-77955471833-
dc.author.googleKam Y.L.-
dc.author.googleRhee H.-K.-
dc.author.googleRhim H.-
dc.author.googleBack S.K.-
dc.author.googleNa H.S.-
dc.author.googleChoo H.-Y.P.-
dc.contributor.scopusid박혜영(34972649500;57200273796)-
dc.date.modifydate20220517112928-
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약학대학 > 약학과 > Journal papers
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