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dc.contributor.author김승철-
dc.contributor.author주웅-
dc.date.accessioned2016-08-28T12:08:24Z-
dc.date.available2016-08-28T12:08:24Z-
dc.date.issued2010-
dc.identifier.issn2005-0380-
dc.identifier.otherOAK-6688-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/220881-
dc.description.abstractObjective: Wine has been the focus in the prevention of epithelial ovarian cancer (EOC) development because resveratrol abundant in wine has anti-carcinogenic properties. However, epidemiologic results have been heterogenous in the chemopreventive effect of wine on the development of EOC. Thus, we performed a meta-analysis for comparing EOC risk between wine and never drinkers using previous related studies. Methods: After extensive search of the literature between January 1986 and December 2008, we analyzed 10 studies (3 cohort and 7 case control studies) with 135,871 women, who included 65,578 of wine and 70,293 of never drinkers. Results: In all studies, there was no significant difference in EOC risk between wine and never drinkers (odds ratio [OR], 1.13; 95% confidence interval [CI], 0.92 to 1.38; random effects). When we performed re-analysis according to the study design, 3 cohort and 7 case control studies showed that there were also no significant differences in EOC risk between wine and never drinkers, respectively (OR, 1.44 and 1.04; 95% CI, 0.74 and 2.82 and 0.88 to 1.22; random effects). In sub-analyses using 2 case-control studies, EOC risk was not different between former and never drinkers (OR, 1.12; 95% CI, 0.87 to 1.44; fixed effect), and between current and former drinkers (OR, 0.74; 95% CI, 0.41 to 1.34; random effects). Conclusion: Although resveratrol, abundantly found in wine, is a promising naturally occurring compound with chemopreventive properties on EOC in preclinical studies, this meta-analysis suggests the epidemiologic evidence shows no association between wine drinking and EOC risk.-
dc.languageEnglish-
dc.titleWine drinking and epithelial ovarian cancer risk: A meta-analysis-
dc.typeArticle-
dc.relation.issue2-
dc.relation.volume21-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage112-
dc.relation.lastpage118-
dc.relation.journaltitleJournal of Gynecologic Oncology-
dc.identifier.doi10.3802/jgo.2010.21.2.112-
dc.identifier.wosidWOS:000279481500011-
dc.identifier.scopusid2-s2.0-77954504855-
dc.author.googleKim H.S.-
dc.author.googleKim J.W.-
dc.author.googleShouten L.J.-
dc.author.googleLarsson S.C.-
dc.author.googleChung H.H.-
dc.author.googleKim Y.B.-
dc.author.googleJu W.-
dc.author.googlePark N.H.-
dc.author.googleSong Y.S.-
dc.author.googleKim S.C.-
dc.author.googleKang S.-B.-
dc.contributor.scopusid김승철(35264000100)-
dc.contributor.scopusid주웅(8873659700)-
dc.date.modifydate20230210135401-
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의과대학 > 의학과 > Journal papers
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