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Korean Pediatric/Adolescent Lymphoma - Incidence and Pathologic Characteristics
- Korean Pediatric/Adolescent Lymphoma - Incidence and Pathologic Characteristics
- Lee S.-S.; Kim J.-M.; Ko Y.-H.; Huh J.; Kang C.S.; Kim C.W.; Kang Y.K.; Go J.H.; Kim M.K.; Kim W.-S.; Kim Y.J.; Kim H.-J.; Kim H.K.; Nam J.H.; Moon H.B.; Park C.-K.; Park T.I.; Oh Y.-H.; Lee D.W.; Lee J.S.; Lee J.; Lee H.; Lim S.-C.; Jang K.Y.; Chang H.-K.; Jeon Y.K.; Jung H.R.; Cho M.-S.; Cha H.J.; Choi S.J.; Han J.H.; Hong S.H.; Kim I.
- Ewha Authors
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- Korean Journal of Pathology
- Korean Journal of Pathology vol. 44, no. 2, pp. 117 - 124
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- Background: The Hematopathology Study Group of the Korean Society of Pathologists conducted a nation-wide retrospective analysis of Korean pediatric lymphoma, to provide pathologic data on pediatric/adolescent lymphoma subtypes and features. Methods: All lymphoma cases of all age groups were collected during a recent 2 year-period (2005-2006) from 32 institutes in Korea. Among 3,686 lymphoma patients, 142 who were age 18 or less were classified according to the World Health Organization (WHO) classification. Results: Among 142 pediatric/adolescent lymphoma patients, Hodgkin lymphoma accounted for 21 (14.8%) and non-Hodgkin lymphoma (NHL) for 121 (85.2%). Hodgkin lymphoma appears to be more common in the pediatric/adolescent age group than in the all-ages group (14.8% vs 4.4%). T- and natural killer cell-NHL was more common in the pediatric/adolescent age group than in the all ages group (46.3% vs 22%). The majority of Korean pediatric/adolescent NHL cases was composed of Burkitt lymphoma, T- or B-lymphoblastic lymphoma, anaplastic large-cell lymphoma, and diffuse large B-cell lymphoma. For lymphoma patients under the age of 6 years, most had B-lymphoblastic or Burkitt lymphoma, which commonly presented at extranodal sites. Conclusions: The distribution of lymphoma subtypes in the pediatric/adolescent age group is quite different from the distribution of adults, but it was quite similar to distribution in Western countries.
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