Spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester of pregnancy

Abstract

Study Objective: To compare the spread of subarachnoid sensory block with hyperbaric bupivacaine in second trimester pregnant and non-pregnant women. Design: Prospective study. Setting: University teaching hospital. Patients: 44 ASA physical status I and II women patients, 22 of whom were in their second trimester of pregnancy undergoing cervical cerclage, and 22 non-pregnant women scheduled for perianal surgery. Interventions: The extent of sensory block and hemodynamic changes were assessed. Measurements: Number of dermatomes blocked was determined by testing for pinprick; systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured at 3, 5, 10, 15, 30 and 60 minutes. Main Results: Maximal sensory block was higher in the second trimester of the pregnant group by three dermatomes than the non-pregnant group. There were no statistically significant differences in SBP, DBP, or HR changes between the groups. Conclusion: Pregnant women in the second trimester exhibit enhanced spread of spinal analgesia with hyperbaric bupivacaine more so than non-pregnant women. © 2009 Elsevier Inc. All rights reserved.