View : 869 Download: 0
When is electrical cortical stimulation more likely to produce afterdischarges?
- Title
- When is electrical cortical stimulation more likely to produce afterdischarges?
- Authors
- Lee H.W.; Webber W.R.S.; Crone N.; Miglioretti D.L.; Lesser R.P.
- Ewha Authors
- 이향운
- SCOPUS Author ID
- 이향운
- Issue Date
- 2010
- Journal Title
- Clinical Neurophysiology
- ISSN
- 1388-2457
- Citation
- Clinical Neurophysiology vol. 121, no. 1, pp. 14 - 20
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Objective: To study when afterdischarges (ADs) are more likely to occur during cortical stimulation. Methods: We examined 6250 electrical stimulation trials in 13 patients with subdural electrodes, studying whether AD occurrence during a trial was influenced by electrode pair stimulated or AD occurrence during the previous trial. In total 545 electrodes were stimulated, 119 frontal (pre-perirolandic), 289 perirolandic, 36 parietal (post-perirolandic), 95 temporal, and 6 occipital. Results: When the same electrode pair was stimulated as the prior trial, 19% produced ADs compared to 5% of trials when a different electrodes pair was stimulated (p < 0.0001). When trials showed ADs, and the next trial stimulated the same electrode pair, ADs occurred in 46% of cases, compared to 13% of trials following trials without ADs (p < 0.0001). AD probability decreased with increased inter-trial interval length only when the prior trial was at the same electrode pair and had produced an AD (p = 0.001). AD probability increased with stimulation duration, whether the trial followed a trial with (p < 0.001) or without (p < 0.0001) an AD. Conclusions: ADs were more likely to occur when an electrode pair showed ADs and was stimulated again, especially when stimulating after short inter-trial intervals or for longer duration. Significance: When ADs occur, waiting about a minute before resuming stimulation might lessen the likelihood of AD recurrence. © 2009 International Federation of Clinical Neurophysiology.
- DOI
- 10.1016/j.clinph.2009.10.001
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML