Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 신동해 | - |
dc.date.accessioned | 2016-08-28T12:08:47Z | - |
dc.date.available | 2016-08-28T12:08:47Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1744-3091 | - |
dc.identifier.other | OAK-6250 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220512 | - |
dc.description.abstract | d,d-Heptose-1,7-bisphosphate phosphatase (GmhB), which is involved in the third step of the NDP-heptose biosynthesis pathway, converts d,d-heptose-1,7 - bisphosphate to d,d-heptose-1-phosphate. This biosynthesis pathway is a target for new antibiotics or antibiotic adjuvants for Gram-negative pathogens. Burkholderia thailandensis is a useful surrogate organism for studying the pathogenicity of melioidosis owing to its extensive genomic similarity to B. pseudomallei. Melioidosis caused by B. pseudomallei is a serious invasive disease of animals and humans in tropical and subtropical areas. In this study, GmhB has been cloned, expressed, purified and crystallized. X-ray data have also been collected to 2.50 Å resolution using synchrotron radiation. The crystal belonged to space group P6, with unit-cell parameters a = 243.2, b = 243.2, c = 41.1 Å. © 2010 International Union of Crystallography All rights reserved. | - |
dc.language | English | - |
dc.title | A preliminary X-ray study of d,d-heptose-1,7-bisphosphate phosphatase from Burkholderia thailandensis E264 | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 66 | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 160 | - |
dc.relation.lastpage | 162 | - |
dc.relation.journaltitle | Acta Crystallographica Section F: Structural Biology and Crystallization Communications | - |
dc.identifier.doi | 10.1107/S1744309109042614 | - |
dc.identifier.wosid | WOS:000274085600009 | - |
dc.identifier.scopusid | 2-s2.0-76349111000 | - |
dc.author.google | Kim M.-S. | - |
dc.author.google | Shin D.H. | - |
dc.contributor.scopusid | 신동해(57217374185) | - |
dc.date.modifydate | 20230208115524 | - |