Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경효 | * |
dc.date.accessioned | 2016-08-28T12:08:41Z | - |
dc.date.available | 2016-08-28T12:08:41Z | - |
dc.date.issued | 2010 | * |
dc.identifier.issn | 1011-8934 | * |
dc.identifier.other | OAK-6184 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220450 | - |
dc.description.abstract | A meta-analysis was performed on the immunogenicity of Haemophilus influenzae type b (Hib) conjugate vaccines after 2 (2 and 4 months) and 3 doses (2, 4, and 6 months) in Korean infants. A database search of MEDLINE, KoreaMed, and Korean Medical Database was done. The primary outcome measure was the proportion of infants with anti-polyribosylribitol phosphate (PRP) concentrations ≥1.0 mg/mL. Eight studies including eleven trials were retrieved. One trial reported on the diphtheria toxoid conjugate vaccine (PRP-D) and 2 trials each on the mutant diphtheria toxin (PRP-CRM) and Neisseria meningitidis outer-membrane protein (PRP-OMP) conjugate vaccine. Heterogeneity in study designs between trials on PRP-CRM was noted and one trial reported on a monovalent and another on a combination PRPOMP vaccine. Thus, a meta-analysis was conducted only on the tetanus toxoid conjugate vaccine (PRP-T). After a primary series of 2 doses and 3 doses, 80.6% (95% confidence interval [CI]; 76.0-85.1%) and 95.7% (95% CI; 94.0-98.0%) of infants achieved an antibody level ≥1.0 mg/mL, respectively. The immunogenic response to the PRP-T vaccine was acceptable after a primary series of 3 doses and also 2 doses. A reduced number of doses as a primary series could be carefully considered in Korean infants. © 2010 The Korean Academy of Medical Sciences. | * |
dc.language | English | * |
dc.title | Immunogenicity of haemophilus influenzae Type b Conjugate Vaccines in Korean Infants: A Meta-analysis | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 25 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 90 | * |
dc.relation.lastpage | 96 | * |
dc.relation.journaltitle | Journal of Korean Medical Science | * |
dc.identifier.doi | 10.3346/jkms.2010.25.1.90 | * |
dc.identifier.wosid | WOS:000273367200016 | * |
dc.identifier.scopusid | 2-s2.0-77949327232 | * |
dc.author.google | Lee H. | * |
dc.author.google | Hahn S. | * |
dc.author.google | Lee H.J. | * |
dc.author.google | Kim K.-H. | * |
dc.contributor.scopusid | 김경효(35448653000) | * |
dc.date.modifydate | 20240301081003 | * |