Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 손연수 | * |
dc.contributor.author | 정병문 | * |
dc.date.accessioned | 2016-08-28T12:08:07Z | - |
dc.date.available | 2016-08-28T12:08:07Z | - |
dc.date.issued | 2008 | * |
dc.identifier.issn | 1744-683X | * |
dc.identifier.other | OAK-5265 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/220108 | - |
dc.description.abstract | Well-defined nanostructural control from biological motifs is gaining attention among materials scientists. We are reporting that the β-sheet structure of l-polyalanine plays a critical role in developing a fibrous nanostructure as well as the sol-to-gel transition of amphiphilic poly(ethylene glycol)-l/or dl-polyalanine diblock copolymers. l-isomers underwent transitions from random coils to β-sheets, and to nanofibers as the polymer concentration increased, whereas the dl-isomer remained as a random coil structure without developing any specific nanostructure. At high polymer concentrations, the aqueous polymer solutions underwent a sol-to-gel transition as the temperature increased, a so called reverse thermal gelation. The l-isomer with a preassembled β-sheet secondary structure facilitates the sol-to-gel transition rather than the dl-isomer with a random coil structure. Thus, only the l-isomer showed a sol-to-gel transition in the physiologically important range of 20-40 °C. This report provides fundamental information on the relationship between hierarchical structures of polypeptides and the thermosensitive sol-gel transition of the polypeptide aqueous solution. © 2008 The Royal Society of Chemistry. | * |
dc.language | English | * |
dc.title | Significance of secondary structure in nanostructure formation and thermosensitivity of polypeptide block copolymers | * |
dc.type | Article | * |
dc.relation.issue | 12 | * |
dc.relation.volume | 4 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 2383 | * |
dc.relation.lastpage | 2387 | * |
dc.relation.journaltitle | Soft Matter | * |
dc.identifier.doi | 10.1039/b809116a | * |
dc.identifier.wosid | WOS:000261726400011 | * |
dc.identifier.scopusid | 2-s2.0-56049119401 | * |
dc.author.google | Choi Y.Y. | * |
dc.author.google | Joo M.K. | * |
dc.author.google | Sohn Y.S. | * |
dc.author.google | Jeong B. | * |
dc.contributor.scopusid | 손연수(7201971323) | * |
dc.contributor.scopusid | 정병문(7102237959) | * |
dc.date.modifydate | 20240118155902 | * |