View : 280 Download: 0
Combined experimental and theoretical approach to understand the reactivity of a mononuclear Cu(II)-hydroperoxo complex in oxygenation reactions
- Combined experimental and theoretical approach to understand the reactivity of a mononuclear Cu(II)-hydroperoxo complex in oxygenation reactions
- Kamachi T.; Lee Y.-M.; Nishimi T.; Cho J.; Yoshizawa K.; Nam W.
- Ewha Authors
- 남원우; 조재흥; 이용민
- SCOPUS Author ID
- 남원우; 조재흥; 이용민
- Issue Date
- Journal Title
- Journal of Physical Chemistry A
- Journal of Physical Chemistry A vol. 112, no. 50, pp. 13102 - 13108
- SCI; SCIE; SCOPUS
- Document Type
Show the fulltext
- A copper(II) complex bearing a pentadentate ligand, [Cu II(N4Py) (CF 3SO 3) 2] (1) (N4Py = N, N-bis(2- pyridylmethyl)bis(2-pyridyl)methylamine), was synthesized and characterized with various spectroscopic techniques and X-ray crystallography. A mononuclear Cu II-hydroperoxo complex, [Cu II(N4Py)(OOH)] + (2), was then generated in the reaction of 1 and H 2O 2 in the presence of base, and the reactivity of the intermediate was investigated in the oxidation of various substrates at -40 °C. In the reactivity studies, 2 showed a low oxidizing power such that 2 reacted only with triethylphosphine but not with other substrates such as thioanisole, benzyl alcohol, 1, 4-cyclohexadiene, cyclohexene, and cyclohexane. In theoretical work, we have conducted density functional theory (DFT) calculations on the epoxidation of ethylene by 2 and a [Cu III(N4Py)(O)] + intermediate (3) at the B3LYP level. The activation barrier is calculated to be 39.7 and 26.3 kcal/mol for distal and proximal oxygen attacks by 2, respectively. This result indicates that the direct ethylene epoxidation by 2 is not a plausible pathway, as we have observed in the experimental work. In contrast, the ethylene epoxidation by 3 is a downhill and low-barrier process. We also found that 2 cannot be a precursor to 3, since the homolytic cleavage of the O-O bond of 2 is very endothermic (i.e., 42 kcal/mol). On the basis of the experimental and theoretical results, we conclude that a mononuclear Cu II-hydroperoxo species bearing a pentadentate N5 ligand is a sluggish oxidant in oxygenation reactions. © 2008 American Chemical Society.
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
- Files in This Item:
There are no files associated with this item.
- RIS (EndNote)
- XLS (Excel)
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.