Bulletin of the Korean Chemical Society vol. 29, no. 10, pp. 1977 - 1982
SCI; SCIE; SCOPUS; KCI
Novel bicyclo[3.1.0]hexanyl purine nucleoside analogues were synthesized as potential antiherpetic agents via a bicyclo[3.1.0]hexanol (±)-8, which was prepared using a highly efficient carbenoid cycloaddition reaction. A highly diastereoselective reduction of ketone and a Mitsunobu reaction for the condensation of glycosyl donor (±)-12 with 6-chloropurine were employed.