Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정낙신 | - |
dc.contributor.author | 최원준 | - |
dc.date.accessioned | 2016-08-28T12:08:55Z | - |
dc.date.available | 2016-08-28T12:08:55Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1525-7770 | - |
dc.identifier.other | OAK-4734 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219985 | - |
dc.description.abstract | On the basis of high binding affinity of 3′-aminoadenosine derivatives 2b at the human A3 adenosine receptor (AR), 3′- acetamidoadenosine derivatives 3a-e were synthesized from 1,2:5,6-di-O- isopropylidene-D-glucose via stereoselective hydroboration as a key step. Although all synthesized compounds were totally devoid of binding affinity at the human A3AR, our results revealed that 3′-position of adenosine can only be tolerated with small size of a hydrogen bonding donor like hydroxyl or amino group in the binding site of human A3AR. Copyright © Taylor & Francis Group, LLC. | - |
dc.language | English | - |
dc.title | Synthesis of 3′-acetamidoadenosine derivatives as potential A 3 adenosine receptor agonists | - |
dc.type | Article | - |
dc.relation.issue | 4 | - |
dc.relation.volume | 27 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 408 | - |
dc.relation.lastpage | 420 | - |
dc.relation.journaltitle | Nucleosides, Nucleotides and Nucleic Acids | - |
dc.identifier.doi | 10.1080/15257770801944436 | - |
dc.identifier.wosid | WOS:000254867900007 | - |
dc.identifier.scopusid | 2-s2.0-42049122671 | - |
dc.author.google | Chun M.W. | - |
dc.author.google | Choi S.W. | - |
dc.author.google | Kang T.K. | - |
dc.author.google | Choi W.J. | - |
dc.author.google | Kim H.O. | - |
dc.author.google | Gao Z.-G. | - |
dc.author.google | Jacobson K.A. | - |
dc.author.google | Jeong L.S. | - |
dc.contributor.scopusid | 정낙신(16028528200) | - |
dc.contributor.scopusid | 최원준(55732412300;57211762651) | - |
dc.date.modifydate | 20230627112239 | - |