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A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata
- Title
- A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata
- Authors
- Han A.-R.; Kim J.-B.; Lee J.; Nam J.-W.; Lee I.-S.; Shim C.-K.; Lee K.-T.; Seo E.-K.
- Ewha Authors
- 서은경; 한아름
- SCOPUS Author ID
- 서은경; 한아름
- Issue Date
- 2007
- Journal Title
- Chemical and Pharmaceutical Bulletin
- ISSN
- 0009-2363
- Citation
- Chemical and Pharmaceutical Bulletin vol. 55, no. 8, pp. 1270 - 1273
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- A new flavanone glycoside, (2R)-5-hydroxy-4′-methoxyflavanone-7-O- {β-glucopyranosyl-(1→2)-β-glucopyranoside} (1), was isolated from the EtOAc extract of dried immature fruit of Poncirus trifoliata, together with three known compounds, (2S)-poncirin (2), (2S)-naringin (3), and (2S)-poncirenin (4). The structure of compound 1 was elucidated by spectroscopic data analysis, including 1D and 2D NMR experiments. Among the isolates, compound 2 exhibited considerable inhibitory activity against lipopolysaccharide (LPS)-induced prostaglandin E2 (PGE2) and interleukin-6 (IL-6) production, and mRNA expression in RAW 264.7 murine macrophage cells. © 2007 Pharmaceutical Society of Japan.
- DOI
- 10.1248/cpb.55.1270
- Appears in Collections:
- 약학대학 > 약학과 > Journal papers
- Files in This Item:
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