View : 764 Download: 0

Full metadata record

DC Field Value Language
dc.contributor.author손연수*
dc.contributor.author이화정*
dc.date.accessioned2016-08-28T12:08:42Z-
dc.date.available2016-08-28T12:08:42Z-
dc.date.issued2007*
dc.identifier.issn0960-894X*
dc.identifier.otherOAK-4050*
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/219862-
dc.description.abstractIn order to develop a new gene delivery vector, a novel cationic poly(organophosphazene) was synthesized by stepwise nucleophilic substitutions of poly(dichlorophosphazene) with a hydrophilic methoxy-poly(ethylene glycol) (MPEG) as a shielding group and a branched tetra(l-lysine), LysLys(LysEt)2, as a cationic moiety. The cationic polymer has shown to form a polyplex by DNA condensation and very low in vitro cytotoxicity probably due to the shielding effect of MPEG, which provides a basis for improving the low gene transfection yield of cationic polyphosphazenes. © 2007 Elsevier Ltd. All rights reserved.*
dc.languageEnglish*
dc.titleA tetra(l-lysine)-grafted poly(organophosphazene) for gene delivery*
dc.typeArticle*
dc.relation.issue11*
dc.relation.volume17*
dc.relation.indexSCI*
dc.relation.indexSCIE*
dc.relation.indexSCOPUS*
dc.relation.startpage2975*
dc.relation.lastpage2978*
dc.relation.journaltitleBioorganic and Medicinal Chemistry Letters*
dc.identifier.doi10.1016/j.bmcl.2007.03.069*
dc.identifier.wosidWOS:000247052900003*
dc.identifier.scopusid2-s2.0-34247871415*
dc.author.googleJun Y.J.*
dc.author.googleKim J.H.*
dc.author.googleChoi S.J.*
dc.author.googleLee H.J.*
dc.author.googleJun M.J.*
dc.author.googleSohn Y.S.*
dc.contributor.scopusid손연수(7201971323)*
dc.contributor.scopusid이화정(57102029300)*
dc.date.modifydate20240118154655*
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

BROWSE