Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상국 | * |
dc.contributor.author | 서은경 | * |
dc.contributor.author | 한아름 | * |
dc.date.accessioned | 2016-08-28T11:08:04Z | - |
dc.date.available | 2016-08-28T11:08:04Z | - |
dc.date.issued | 2006 | * |
dc.identifier.issn | 0163-3864 | * |
dc.identifier.other | OAK-3314 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219696 | - |
dc.description.abstract | A new prenylated chalcone, 3″,3″-dimethylpyrano[3′, 4′]2,4,2′-trihydroxychalcone (1), was isolated from the heartwood of Artocarpus communis. Two flavonoid derivatives, (-)-cycloartocarpin (9) and (-)-cudraflavone A (10), were isolated as new isomers. In addition, eight known flavonoids, isobacachalcone (2), morachalcone A (3), gemichalcones B (4) and C (5), artocarpin (6), cudraflavone C (7), licoflavone C (8), and (2S)-euchrenone a7 (11), were isolated and identified from this plant for the first time. Compounds 1-4, 6, and 11 exhibited potent inhibitory activity on nitric oxide production in RAW264.7 LPS-activated mouse macrophage cells with IC 50 values of 18.8, 6.4, 16.4, 9.3, 18.7, and 12.3, μM, respectively. The structure of compound 1 was elucidated by spectroscopic data analysis, including 1D and 2D NMR experiments. © 2006 American Chemical Society and American Society of Pharmacognosy. | * |
dc.language | English | * |
dc.title | Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 69 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 719 | * |
dc.relation.lastpage | 721 | * |
dc.relation.journaltitle | Journal of Natural Products | * |
dc.identifier.doi | 10.1021/np0600346 | * |
dc.identifier.wosid | WOS:000237343400046 | * |
dc.identifier.scopusid | 2-s2.0-33744502095 | * |
dc.author.google | Han A.-R. | * |
dc.author.google | Kang Y.-J. | * |
dc.author.google | Windono T. | * |
dc.author.google | Lee S.K. | * |
dc.author.google | Seo E.-K. | * |
dc.contributor.scopusid | 이상국(36067620500) | * |
dc.contributor.scopusid | 서은경(7005953758) | * |
dc.contributor.scopusid | 한아름(56278315000;34769874800) | * |
dc.date.modifydate | 20240130112016 | * |