Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 임원정 | - |
dc.date.accessioned | 2016-08-28T11:08:03Z | - |
dc.date.available | 2016-08-28T11:08:03Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0161-8105 | - |
dc.identifier.other | OAK-3294 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/219689 | - |
dc.description.abstract | Study Objective: We investigated the short-term effectiveness of continuous positive airway pressure (CPAP) and oxygen in improving sleep quality in patients with obstructive sleep apnea (OSA). Design: Randomized, double-blind, placebo-controlled, parallel study. Setting: General Clinical Research Center at a university hospital. Patients: Seventy-six patients with untreated OSA. Interventions: Patients were randomly assigned to 1 of 3 treatments (CPAP, placebo-CPAP, or nocturnal oxygen at 3 L per minute) for 2 weeks. Sleep quality was assessed at baseline and after 1 and 14 days of therapy. Repeated-measures analysis of variance was used to evaluate treatment and time effects, and their interaction. Measurements and Results: Sixty-three patients completed the protocol. When compared with placebo-CPAP and nocturnal oxygen, CPAP increased rapid eye movement (REM) sleep and significantly reduced stage 1 sleep and the number of stage shifts (p < .003). CPAP improved, to within normal limits, the apnea-hypopnea index, total arousal index, and mean oxyhemoglobin saturation (p < .001). The effects of CPAP were apparent during the first night of therapy. Oxygen improved only mean nocturnal saturation (p = .009). CPAP had no significant effect on stage 2 sleep or slow-wave sleep. Conclusions: CPAP was associated with an improvement in sleep quality in patients with OSA by consolidating sleep, reducing stage 1 sleep, and improving REM sleep. CPAP was effective in correcting the respiratory and arousal abnormalities of OSA. The effectiveness of supplemental oxygen was limited to oxyhemoglobin desaturation. | - |
dc.language | English | - |
dc.title | Effect of continuous positive airway pressure versus supplemental oxygen on sleep quality in obstructive sleep apnea: A placebo-CPAP - Controlled study | - |
dc.type | Article | - |
dc.relation.issue | 4 | - |
dc.relation.volume | 29 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 564 | - |
dc.relation.lastpage | 571 | - |
dc.relation.journaltitle | Sleep | - |
dc.identifier.wosid | WOS:000237061300022 | - |
dc.identifier.scopusid | 2-s2.0-33745804289 | - |
dc.author.google | Loredo J.S. | - |
dc.author.google | Ancoli-Israel S. | - |
dc.author.google | Lim E.-J. | - |
dc.author.google | Lim W.J. | - |
dc.author.google | Dimsdale J.E. | - |
dc.contributor.scopusid | 임원정(8404516800) | - |
dc.date.modifydate | 20180329110650 | - |