A fluorescein derivative for nanomolar aqueous copper and monitoring copper ion uptake by transferrin and amyloid precursor protein

Abstract

A new fluorescent chemosensor based on the fluorescein derivative effectively recognizes Cu 2+ in nanomolar range at pH 7.4. The Cu 2+ ion uptake by transferrin and amyloid precursor protein was monitored using the title fluorescent chemosensor. © 2005 Elsevier Ltd. All rights reserved.