Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 전길자 | - |
dc.date.accessioned | 2016-08-28T11:08:18Z | - |
dc.date.available | 2016-08-28T11:08:18Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0918-6158 | - |
dc.identifier.other | OAK-293 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/218559 | - |
dc.description.abstract | The mechanism of phagocytic activity of the ethyl alcohol fraction of Cervus nippon (CN-E) was investigated in vivo. The administration of CN-E (100 mg/kg, p.o.) enhanced lucigenin chemiluminescence and the engulfment of fluorescein-conjugated E. coli particles in murine peritoneal macrophages. Phagocytic activity was suppressed by the treatment of S-nitrosoglutathione (GSNO) which is an exogenous nitric oxide donor depending on the concentration of dose. CN-E suppressed the production of nitric oxide and enhanced the concentration in [Ca2+](i). The enhancement in [Ca2+](i) was diminished by the treatment of EGTA. These results indicate that CN-E enhances the phagocytic activity of murine peritoneal macrophage via a suppression of nitric oxide production and an increase in [Ca2+](i). | - |
dc.language | English | - |
dc.title | Phagocytic activity of ethyl alcohol fraction of deer antler in murine peritoneal macrophage | - |
dc.type | Article | - |
dc.relation.issue | 9 | - |
dc.relation.volume | 22 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 932 | - |
dc.relation.lastpage | 935 | - |
dc.relation.journaltitle | Biological and Pharmaceutical Bulletin | - |
dc.identifier.wosid | WOS:000082660800009 | - |
dc.identifier.scopusid | 2-s2.0-0032821186 | - |
dc.author.google | Suh J.-S. | - |
dc.author.google | Eun J.-S. | - |
dc.author.google | So J.-N. | - |
dc.author.google | Seo J.-T. | - |
dc.author.google | Jhon G.-J. | - |
dc.contributor.scopusid | 전길자(6701488476) | - |
dc.date.modifydate | 20180301081000 | - |