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6-Arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation
- Title
- 6-Arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation
- Authors
- Ryu C.-K.; Jung S.-H.; Lee J.-A.; Kim H.-J.; Lee S.-H.; Chung J.-H.
- Ewha Authors
- 유충규; 김화정
- SCOPUS Author ID
- 유충규; 김화정
- Issue Date
- 1999
- Journal Title
- Bioorganic and Medicinal Chemistry Letters
- ISSN
- 0960-894X
- Citation
- Bioorganic and Medicinal Chemistry Letters vol. 9, no. 17, pp. 2469 - 2472
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- 6-Arylamino-5,8-quinolinediones 3 and 7-arylamino-5,8-isoquinolinediones 4 were synthesized as inhibitors of endothelium-dependent vasorelaxation. The quinones inhibited the vasorelaxation of rat aorta with the endothelium. Among them, the quinones 3a, 3b, 3f, 4b, 4d and 4g strongly inhibited the vasorelaxation.
- DOI
- 10.1016/S0960-894X(99)00411-4
- Appears in Collections:
- 약학대학 > 약학과 > Journal papers
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