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Metabolic health is more closely associated with prevalence of cardiovascular diseases or stroke than obesity A cross-sectional study in Korean populations
- Title
- Metabolic health is more closely associated with prevalence of cardiovascular diseases or stroke than obesity A cross-sectional study in Korean populations
- Authors
- Byun, A. Ri; Kwon, Seungwon; Lee, Sang Wha; Shim, Kyung Won; Lee, Hong Soo
- Ewha Authors
- 이상화; 이홍수; 심경원; 변아리
- SCOPUS Author ID
- 이상화; 이홍수; 심경원; 변아리
- Issue Date
- 2016
- Journal Title
- MEDICINE
- ISSN
- 0025-7974
1536-5964
- Citation
- MEDICINE vol. 95, no. 24
- Keywords
- cardiovascular disease; metabolically healthy obese; obesity; risk factor; stroke prevalence
- Publisher
- LIPPINCOTT WILLIAMS &
WILKINS
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Mounting evidence suggests that not all obese subjects are at increased cardiovascular risk. However, the relationship between the metabolically healthy obese (MHO) phenotype and cardiovascular diseases (CVDs) or stroke remains unclear. Therefore, we retrospectively investigated the prevalence of CVDs or stroke according to metabolic health with obese. We studied 3695 subjects (40-85 years) from the Fifth Korean National Health and Nutrition Examination Survey. Participants were divided into 2 groups and 6 subgroups based on the body mass index (BMI) and metabolic syndrome (MetS) components: healthy (exhibiting none of the 5 MetS components) with the followings: healthy-normal weight (BMI <23 kg/m(2)), healthy-overweight (BMI=23-24.9 kg/m(2)), and healthy-obese (BMI >= 25kg/m(2)); and unhealthy (exhibiting 2 or more MetS components) with the followings: unhealthy-normal weight, unhealthy-overweight, and unhealthy-obese. In the healthy group (n=1726), there were 76 CVDs or stroke patients (4.4%), whereas in the unhealthy group (n=1969), there were 170 (8.6%). The prevalence was significantly different between the 2 groups (P<0.001). However, the prevalence was not significantly different among healthy subgroups (P=0.4072). The prevalence in unhealthy subgroups also demonstrated no statistically significant difference (P=0.3798). We suggest that the prevalence of CVDs or stroke is different between metabolically healthy and unhealthy phenotype. Furthermore, MHO did not reveal higher CVDs or stroke prevalence rather than metabolically healthy other groups. Additional cohort studies are needed to explain causality between CVDs or stroke incidence and subjects exhibiting the MHO phenotype.
- DOI
- 10.1097/MD.0000000000003902
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
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