View : 685 Download: 0
Body burden of persistent organic pollutants on hypertension: a meta-analysis
- Title
- Body burden of persistent organic pollutants on hypertension: a meta-analysis
- Authors
- Park, Su Hyun; Lim, Jung-eun; Park, Hyesook; Jee, Sun Ha
- Ewha Authors
- 박혜숙
- SCOPUS Author ID
- 박혜숙
- Issue Date
- 2016
- Journal Title
- ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- ISSN
- 0944-1344
1614-7499
- Citation
- ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH vol. 23, no. 14, pp. 14284 - 14293
- Keywords
- Blood pressure; Hypertension; Endocrine disruptors; Polychlorinated biphenyls
- Publisher
- SPRINGER HEIDELBERG
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Except the known risk factors for hypertension, several studies have suggested that exposure to persistent organic pollutants (POPs), endocrine disrupting chemicals, could be associated with an increased risk of hypertension. In this study, we performed a meta-analysis to summarize the existing epidemiological studies to investigate the association between POPs concentration and risk of hypertension. Based on comprehensive literature search results (PubMed, EMBASE, and KoreaMed), a meta-analysis of 11 articles was performed using a random-effects model. While we observed no significant association between the sum of non-dioxin-like PCBs and the risk of hypertension (OR = 1.00; 95 % CI 0.89, 1.12), the sum of dioxin-like PCBs was associated with a significantly increased risk of hypertension (OR = 1.45; 95 % CI 1.00, 2.12). High p,p'-DDE level was also significantly associated with the increased risk of hypertension. When subgroup analyses were carried out for studies which analyzed POPs concentrations using high-resolution gas chromatography/high-resolution mass spectrometry, the overall pooled estimate ORs increased with decreased heterogeneity, providing it as a possible heterogeneity source (OR = 1.36; 95 % CI 1.21, 1.52; I-2 = 42.8 %; p = 0.045). This study suggested that the concentration of certain POPs, especially dioxin-related compounds, was associated with the risk of hypertension.
- DOI
- 10.1007/s11356-016-6568-6
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML