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Risk of Advanced Colorectal Neoplasia According to the Number of High-Risk Findings at Index Colonoscopy: A Korean Association for the Study of Intestinal Disease (KASID) Study
- Title
- Risk of Advanced Colorectal Neoplasia According to the Number of High-Risk Findings at Index Colonoscopy: A Korean Association for the Study of Intestinal Disease (KASID) Study
- Authors
- Jung, Yoon Suk; Park, Dong Il; Kim, Won Hee; Eun, Chang Soo; Park, Soo-Kyung; Ko, Bong Min; Seo, Geom Seog; Cha, Jae Myung; Park, Jae Jun; Kim, Kyeong Ok; Moon, Chang Mo; Jung, Yunho; Kim, Eun Soo; Jeon, Seong Ran; Lee, Chang Kyun
- Ewha Authors
- 문창모
- SCOPUS Author ID
- 문창모
- Issue Date
- 2016
- Journal Title
- DIGESTIVE DISEASES AND SCIENCES
- ISSN
- 0163-2116
1573-2568
- Citation
- DIGESTIVE DISEASES AND SCIENCES vol. 61, no. 6, pp. 1661 - 1668
- Keywords
- Colonoscopy; High-risk adenoma; Colorectal neoplasia; Recurrence
- Publisher
- SPRINGER
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Data regarding outcomes for patients with multiple findings for high-risk adenomas are scarce. To compare the risk for colorectal neoplasm (CRN) recurrence according to the number of high-risk findings. This was a retrospective and multicenter study. Patients who had one or more high-risk adenomas at the index colonoscopy and underwent follow-up colonoscopy 2.5 or more years after the index colonoscopy were included. The number of high-risk findings was defined as follows: number of adenomas larger than 1 cm + number of adenomas with HGD + number of adenomas with a villous component + existence (counted as 1) or nonexistence (counted as 0) of three or more adenomas. A total of 1646 patients were included, and the mean duration between index and follow-up colonoscopy was approximately 4 years. The cumulative incidence rate of recurrent advanced CRN in patients with three or more high-risk findings was higher than that in patients with one or two high-risk findings (p < 0.001). However, the difference in 3-year cumulative incidence rates of recurrent advanced CRN between the two groups was not great, although it was statistically significant (4.8 vs. 2.3 %, p = 0.039). A 3-year surveillance interval for patients with multiple high-risk findings, regardless of the number of high-risk findings, appears reasonable.
- DOI
- 10.1007/s10620-016-4038-0
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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