Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 정지향 | * |
dc.date.accessioned | 2016-08-27T04:08:11Z | - |
dc.date.available | 2016-08-27T04:08:11Z | - |
dc.date.issued | 2015 | * |
dc.identifier.issn | 1420-8008 | * |
dc.identifier.issn | 1421-9824 | * |
dc.identifier.other | OAK-15676 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/217630 | - |
dc.description.abstract | Background/Aims: The aims of this study were to determine baseline factors related to the progression of subjective memory impairment (SMI) in elderly subjects and to develop a new modeling scale to predict progression. Methods: Elderly subjects with SMI were recruited from the nationwide Clinical Research Centers for Dementia of South Korea (CREDOS) multicenter cohort and divided into two groups: (1) progressed to mild cognitive impairment or Alzheimer's disease or (2) stable without progression. Baseline clinical characteristics were compared between the groups, and the most relevant predictors of progression were assessed. A new modeling scale combining the predictors was developed. Results: In total, 129 subjects with SMI were analyzed. The follow-up duration was 0.5-4.7 years, and the median time to event was 3.64 years. The progressing group (n = 29) differed from the stable group (n = 100) in terms of baseline age, apolipoprotein E4 (APOE4) status, and some cognitive domains. Older age, a lower Mini-Mental State Examination recall score, APOE4 carrier, and a lower verbal delayed recall score were the most relevant predictors of progression, and a new modeling scale with these 4 predictors provided a better explanation of progression. Conclusion: SMI subjects with a higher risk of progression can be identified using a new modeling scale and might need further evaluations and more frequent follow-up. (C) 2015 S. Karger AG, Basel | * |
dc.language | English | * |
dc.publisher | KARGER | * |
dc.subject | Subjective memory impairment | * |
dc.subject | Mild cognitive impairment | * |
dc.subject | Alzheimer's disease | * |
dc.subject | Progression | * |
dc.subject | Predictors | * |
dc.title | Predictors of Clinical Progression of Subjective Memory Impairment in Elderly Subjects: Data from the Clinical Research Centers for Dementia of South Korea (CREDOS) | * |
dc.type | Article | * |
dc.relation.issue | 42067 | * |
dc.relation.volume | 40 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 158 | * |
dc.relation.lastpage | 165 | * |
dc.relation.journaltitle | DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | * |
dc.identifier.doi | 10.1159/000430807 | * |
dc.identifier.wosid | WOS:000360931000005 | * |
dc.author.google | Hong, Yun Jeong | * |
dc.author.google | Yoon, Bora | * |
dc.author.google | Shim, Yong S. | * |
dc.author.google | Kim, Seon-Ok | * |
dc.author.google | Kim, Hwa Jung | * |
dc.author.google | Choi, Seong Hye | * |
dc.author.google | Jeong, Jee Hyang | * |
dc.author.google | Yoon, Soo Jin | * |
dc.author.google | Yang, Dong Won | * |
dc.author.google | Lee, Jae-Hong | * |
dc.contributor.scopusid | 정지향(7402045750;57192068764) | * |
dc.date.modifydate | 20240123101416 | * |