Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages

Abstract

Three new flavonostilbenes, alopecurones M-O (1-3), were isolated from the root bark of Sophora alopecuroides L. together with 21 known compounds. The structures of the isolated compounds were elucidated by using NMR, MS, and CD spectroscopic data. All isolates were evaluated for their potential to inhibit LPS-induced nitric oxide production in RAW 264.7 cells. (C) 2015 Elsevier Ltd. All rights reserved.