Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오억수 | - |
dc.date.accessioned | 2016-08-27T02:08:51Z | - |
dc.date.available | 2016-08-27T02:08:51Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.other | OAK-4880 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/216249 | - |
dc.description.abstract | Syndecan-3 is a cell-surface heparan sulfate proteoglycan, which performs a variety of functions during cell adhension process. It is also a coreceptor for growth factor, mediating cell-cell and cell-matrix interaction. Syndecan-3 contains a cytoplasmic domain potentially associated with the cytoskeleton. Syndecan-3 is specifically expressed in neuron cell and has related to neuron cell differentiation and development of actin filament in cell migration. Syndecans each have a unique, central, and variable (V) region in their cytoplasmic domains. And that region of syndecan-3 may modulate the interactions of the conserved Cl regions of the cytoplasmic domains by tyrosine phosphorylation. Cytoplasmic domain of syndecan-3 has been synthesized for NMR structural studies. The solution structure of syndecan-3 cytoplasmic domain has been determined by two-dimensional NMR spectroscopy and simulated-annealing calculation. The cytoplasmic domain of the syndecan proteins has a tendency to form a dimmer conformation with a central cavity, however, that of syndecan-3 demonstrated a monomer conformation with a flexible region near C-terminus. The structural information might add knowledge about the structure-function relationships among syndecan proteins. | - |
dc.language | English | - |
dc.publisher | KOREAN CHEMICAL SOC | - |
dc.subject | syndecan-3 | - |
dc.subject | proteoglycan | - |
dc.subject | NMR | - |
dc.title | Solution structure of the cytoplasmic domain of syndecan-3 by two-dimensional NMR spectroscopy | - |
dc.type | Article | - |
dc.relation.issue | 5 | - |
dc.relation.volume | 29 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 1013 | - |
dc.relation.lastpage | 1017 | - |
dc.relation.journaltitle | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.identifier.wosid | WOS:000256784600023 | - |
dc.identifier.scopusid | 2-s2.0-45149104063 | - |
dc.author.google | Yeo, In Young | - |
dc.author.google | Koo, Bonkyung | - |
dc.author.google | Oh, Eok-soo | - |
dc.author.google | Han, Inn-Oc | - |
dc.author.google | Lee, Weontae | - |
dc.contributor.scopusid | 오억수(7101967153) | - |
dc.date.modifydate | 20230201093717 | - |