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Synthesis of novel 3 '-deoxy-3 '-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents

Title
Synthesis of novel 3 '-deoxy-3 '-C-hydroxymethyl nucleosides with conformationally rigid sugar moiety as potential antiviral agents
Authors
Chun, MWKim, MJJo, UHKim, JHKim, HDJeong, LS
Ewha Authors
정낙신
SCOPUS Author ID
정낙신scopus
Issue Date
2001
Journal Title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN
1525-7770JCR Link
Citation
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS vol. 20, no. 4-7, pp. 699 - 702
Publisher
MARCEL DEKKER INC
Indexed
SCIE; SCOPUS WOS
Document Type
Article

Proceedings Paper
Abstract
Based on the fact that the ring expanded 3'-C-hydroxymethyl analogue of oxetanocin A exhibited potent antiviral activity, two types of conformationally rigid 3'-C-hydroxymethyl derivatives in which 2'-hydroxyl group is linked to the 4'-position or to the 6'-position were synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose, respectively.
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DOI
10.1081/NCN-100002354
Appears in Collections:
약학대학 > 약학과 > Journal papers
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