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dc.contributor.author李世允-
dc.creator李世允-
dc.date.accessioned2016-08-26T10:08:26Z-
dc.date.available2016-08-26T10:08:26Z-
dc.date.issued1979-
dc.identifier.otherOAK-000000032852-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/200739-
dc.identifier.urihttp://dcollection.ewha.ac.kr/jsp/common/DcLoOrgPer.jsp?sItemId=000000032852-
dc.description.abstract3-formyl rifamycin SV와 L-2-amino-I-butanol을 1 : 1의 몰 비로 20~25℃에서 다음과 같이 반응시켜서 흑자색의 결정을 얻었다. ◁그림 삽입▷(원문을 참조하세요) 이 화합물은 3-formyl rifamycin SV의 -CHO기와 L-2-amino-1-butanol의 -NH₂기 사이에서 Schiff's base가 된 것이며 그 λmax는 312nm, 555nm에 있었고 쉽게 가수분해되어 3-formyl rifamycin SV와 L-2-amino-1-butanol로 되돌아 가는 매우 불안정한 화합물이었다. 그러나 이 Schiff's base를 환원하면 매우 안정된 화합물이 되었으며 그 λmax는 315nm 와 447nm에 있었다.;The new derivative of 3-formyl rifamycin SV. was synthesized from -CHO group of 3-formyl rifamycin sv and -NH₂ group of L-2-amino-l-butanol. The new synthesized schiff's base was 3-(l-hydroxy-2-n-butanyl imino methvl)-rifamycin SV The Schiff's base that was synthesized from 3-formyl rifamycin SV and L-2-amino-l-butanol was signified as schiff's base-L, and the Schiff's base was synthesized from 3-formyl rifamycin SV and D-2-amino-l-butanol as schiff's base-D respectively. The results were as follows : 1. The Schiff's base-L was dark violet crystal, very unstable, and it's absorption maximum was 312nm, 555nm. 2. The schiff's base-L eras readily hydrolyzed to 3-formyl rifamycin SV and L-2-amino-l-butanol. 3. By reduction of the schiff's base-L, very stable, and it's absorption maximum was 315nm, 447nm. 4. As the Schiff's base-L was compared with the Schiff's base-D, the schiff's base-D was different to the Schiff's base-L, and it's absorption maximum 345nm, 555nm. The two Schiff's bases were readily hydrolyzed to 3-formyl rifamycin SV, and the two reducing Schiff's bases were the same compounds of λmax 315nm, 447nm.-
dc.description.tableofcontents論文槪要 = ⅴ Ⅰ. 서론 = 1 Ⅱ. 실험 = 3 A. 실험에 사용한 기구 및 시약 = 3 1. 기구 = 3 2. 시약 = 3 B. 실험방법 = 4 1. Schiff's base의 합성 = 4 2. Thin Layer Chromatoghaphy에 의한 반응생성물의 분리 = 6 Ⅲ. 결과 = 7 A. 반응생성물이 T. L. C에 나타난 spot의 Rf값과 그 색 = 7 B. Schiff's base -L의 Absorption spectrum = 8 C. Schiff's base -D의 Absorption spectrum = 10 D. 3 - formyl rifamycin SV의 IR - Spectrum과 Schiff's base -L의 IR Spectrum = 12 E. Schiff's base-L의 가수분해 = 15 F. Schiff's base-L의 환원 = 18 Ⅳ. 고찰 = 21 Ⅴ. 결론 = 24 참고문헌 = 25 ABSTRACT = 26-
dc.formatapplication/pdf-
dc.format.extent797931 bytes-
dc.languagekor-
dc.publisher이화여자대학교 대학원-
dc.subject3-Formyl Rifamycin SV-
dc.subject유도체-
dc.subject반응생성물-
dc.title3-Formyl Rifamycin SV의 유도체에 관한 연구-
dc.typeMaster's Thesis-
dc.title.translatedStudies on the derivative of 3-Formyl Rifamycin SV-
dc.format.pagevi, 27 p. : 삽도.-
dc.identifier.thesisdegreeMaster-
dc.identifier.major대학원 화학과-
dc.date.awarded1980. 2-
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